BDBM50174832 CHEMBL198562::N-[2-(3'-cyano-biphenyl-4-yl)-ethyl]-N-[(3,5-dichloro-phenylcarbamoyl)-methyl]-3-((S)-3-hydroxy-pyrrolidin-1-yl)-propionamide

SMILES O[C@H]1CCN(CCC(=O)N(CCc2ccc(cc2)-c2cccc(c2)C#N)CC(=O)Nc2cc(Cl)cc(Cl)c2)C1

InChI Key InChIKey=BUGRTZMNHWAJRY-NDEPHWFRSA-N

Data  2 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50174832   

TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50174832(CHEMBL198562 | N-[2-(3'-cyano-biphenyl-4-yl)-ethyl...)
Show SMILES O[C@H]1CCN(CCC(=O)N(CCc2ccc(cc2)-c2cccc(c2)C#N)CC(=O)Nc2cc(Cl)cc(Cl)c2)C1
Show InChI InChI=1S/C30H30Cl2N4O3/c31-25-15-26(32)17-27(16-25)34-29(38)20-36(30(39)10-12-35-11-9-28(37)19-35)13-8-21-4-6-23(7-5-21)24-3-1-2-22(14-24)18-33/h1-7,14-17,28,37H,8-13,19-20H2,(H,34,38)/t28-/m0/s1
Affinity DataKi:  7.20nMAssay Description:Antagonist activity against human MCH1 receptorMore data for this Ligand-Target Pair
TargetMelanin-concentrating hormone receptor 2(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50174832(CHEMBL198562 | N-[2-(3'-cyano-biphenyl-4-yl)-ethyl...)
Show SMILES O[C@H]1CCN(CCC(=O)N(CCc2ccc(cc2)-c2cccc(c2)C#N)CC(=O)Nc2cc(Cl)cc(Cl)c2)C1
Show InChI InChI=1S/C30H30Cl2N4O3/c31-25-15-26(32)17-27(16-25)34-29(38)20-36(30(39)10-12-35-11-9-28(37)19-35)13-8-21-4-6-23(7-5-21)24-3-1-2-22(14-24)18-33/h1-7,14-17,28,37H,8-13,19-20H2,(H,34,38)/t28-/m0/s1
Affinity DataKi: >3.00E+3nMAssay Description:Antagonist activity against human MCH2 receptorMore data for this Ligand-Target Pair