BDBM50175205 CHEMBL200587::N-(4-(4-amino-1-(piperidin-4-yl)-1H-pyrazolo[3,4-d]pyrimidin-3-yl)-2-methoxyphenyl)-2-fluoro-4-(trifluoromethyl)benzamide

SMILES COc1cc(ccc1NC(=O)c1ccc(cc1F)C(F)(F)F)-c1nn(C2CCNCC2)c2ncnc(N)c12

InChI Key InChIKey=FJLCUIPBRCOHAL-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50175205   

TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
Abbott Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM50175205(CHEMBL200587 | N-(4-(4-amino-1-(piperidin-4-yl)-1H...)
Affinity DataIC50:  80nMAssay Description:Inhibitory activity against lckMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Fyn(Homo sapiens (Human))
Abbott Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM50175205(CHEMBL200587 | N-(4-(4-amino-1-(piperidin-4-yl)-1H...)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibitory activity against fynMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
Abbott Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM50175205(CHEMBL200587 | N-(4-(4-amino-1-(piperidin-4-yl)-1H...)
Affinity DataIC50:  50nMAssay Description:Inhibitory activity against anti-CD3 mAb-induced IL2 production in human whole bloodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed