BDBM50175548 CHEMBL198778::N-Hydroxy-2-(4-phenoxy-benzenesulfonylamino)-acetamide
SMILES ONC(=O)CNS(=O)(=O)c1ccc(Oc2ccccc2)cc1
InChI Key InChIKey=YJRJYIQWWPZSTM-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 9 hits for monomerid = 50175548
TargetA disintegrin and metalloproteinase with thrombospondin motifs 5(Homo sapiens (Human))
Universit£
Curated by ChEMBL
Universit£
Curated by ChEMBL
Affinity DataKi: 840nMAssay Description:Inhibition of human recombinant ADAMTS5 using bovine nasal cartilage aggrecan as substrate assessed as inhibition of 1772-AGEG neopeptide formation i...More data for this Ligand-Target Pair
TargetA disintegrin and metalloproteinase with thrombospondin motifs 5(Homo sapiens (Human))
Universit£
Curated by ChEMBL
Universit£
Curated by ChEMBL
Affinity DataIC50: 330nMAssay Description:Inhibition of human recombinant ADAMTS5 expressed in HEK293 cells using Abz-TESEwSRGAIY-Dpa-KK as substrate measured for 2 hrs by fluorometric analys...More data for this Ligand-Target Pair
Affinity DataIC50: 22nMAssay Description:Inhibitory concentration against (MMP-1) matrix metalloproteinase-1More data for this Ligand-Target Pair
TargetMeprin A subunit beta(Homo sapiens)
Fraunhofer Institute For Cell Therapy And Immunology Izi
Curated by ChEMBL
Fraunhofer Institute For Cell Therapy And Immunology Izi
Curated by ChEMBL
Affinity DataIC50: 1.88E+4nMAssay Description:Inhibition of recombinant human meprin beta expressed in yeast using Abz-YVAEAPK(Dnp)G-OH as substrate by fluorescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 0.100nMAssay Description:Inhibition of human recombinant MMP13 using Mca-Lys-Pro- Leu-Gly-Leu-Dap(Dnp)-Ala-Arg-NH2 as substrate incubated for 2 hrs prior to substrate additio...More data for this Ligand-Target Pair
Affinity DataIC50: 0.0400nMAssay Description:Inhibition of human recombinant MMP2 using Mca-Lys-Pro- Leu-Gly-Leu-Dap(Dnp)-Ala-Arg-NH2 as substrate incubated for 2 hrs prior to substrate addition...More data for this Ligand-Target Pair
Affinity DataIC50: 720nMAssay Description:Inhibition of human recombinant MMP1 using Mca-Lys-Pro- Leu-Gly-Leu-Dap(Dnp)-Ala-Arg-NH2 as substrate incubated for 2 hrs prior to substrate addition...More data for this Ligand-Target Pair
TargetA disintegrin and metalloproteinase with thrombospondin motifs 4(Homo sapiens (Human))
Universit£
Curated by ChEMBL
Universit£
Curated by ChEMBL
Affinity DataIC50: 580nMAssay Description:Inhibition of human recombinant ADAMTS4 expressed in HEk293 cells using FAM-AEwLQGRPISIAK-TAMRA as substrate measured for 15 mins by fluorometric ana...More data for this Ligand-Target Pair
Affinity DataIC50: 4nMAssay Description:Inhibition of human recombinant MMP14 catalytic domain using Mca-Lys-Pro- Leu-Gly-Leu-Dap(Dnp)-Ala-Arg-NH2 as substrate incubated for 2 hrs prior to ...More data for this Ligand-Target Pair