BDBM50175894 1-phenethyl-8-((1S,2S)-2-phenyl-cyclohexyl)-1,3,8-triaza-spiro[4.5]decan-4-one::CHEMBL373053

SMILES O=C1NCN(CCc2ccccc2)C11CCN(CC1)[C@H]1CCCC[C@H]1c1ccccc1

InChI Key InChIKey=QYDCMTRUYZGQLR-DQEYMECFSA-N

Data  2 IC50  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50175894   

TargetSodium- and chloride-dependent glycine transporter 1(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50175894(1-phenethyl-8-((1S,2S)-2-phenyl-cyclohexyl)-1,3,8-...)
Affinity DataEC50:  25nMAssay Description:Inhibition of [3H]glycine uptake in cells transfected with human GlyT1 cDNAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNociceptin receptor(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50175894(1-phenethyl-8-((1S,2S)-2-phenyl-cyclohexyl)-1,3,8-...)
Affinity DataIC50: >1.00E+4nMAssay Description:Displacement of [3H]NOP from human NOP receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50175894(1-phenethyl-8-((1S,2S)-2-phenyl-cyclohexyl)-1,3,8-...)
Affinity DataIC50:  3.20E+3nMAssay Description:Displacement of [3H]naloxone from human mu opioid receptor expressed in BHK cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent glycine transporter 2(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50175894(1-phenethyl-8-((1S,2S)-2-phenyl-cyclohexyl)-1,3,8-...)
Affinity DataEC50:  1.80E+4nMAssay Description:Inhibition of [3H]glycine uptake in cells transfected with human GlyT2 cDNAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed