BDBM50175906 1-phenyl-8-((cis,rac)-2-phenyl-cycloheptyl)-1,3,8-triaza-spiro[4.5]decan-4-one::CHEMBL199637

SMILES O=C1NCN(c2ccccc2)C11CCN(CC1)[C@H]1CCCCC[C@H]1c1ccccc1

InChI Key InChIKey=AJYFBSDJLNTJGV-ZEQRLZLVSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50175906   

TargetSodium- and chloride-dependent glycine transporter 1(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50175906(1-phenyl-8-((cis,rac)-2-phenyl-cycloheptyl)-1,3,8-...)
Affinity DataEC50:  1.70E+3nMAssay Description:Inhibition of [3H]glycine uptake in cells transfected with human GlyT1 cDNAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed