BDBM50176364 2-(Acetyl-phenyl-amino)-N-[(S)-2-((S)-3-hydroxy-pyrrolidin-1-yl)-1-phenyl-ethyl]-N-methyl-acetamide::CHEMBL202591

SMILES CN([C@H](CN1CC[C@H](O)C1)c1ccccc1)C(=O)CN(C(C)=O)c1ccccc1

InChI Key InChIKey=SJHKJRARQHDQKM-FCHUYYIVSA-N

Data  2 KI  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50176364   

TargetKappa-type opioid receptor(Homo sapiens (Human))
Adolor

Curated by ChEMBL
LigandPNGBDBM50176364(2-(Acetyl-phenyl-amino)-N-[(S)-2-((S)-3-hydroxy-py...)
Affinity DataKi:  3.80nMAssay Description:Binding affinity to kappa opioid receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
Adolor

Curated by ChEMBL
LigandPNGBDBM50176364(2-(Acetyl-phenyl-amino)-N-[(S)-2-((S)-3-hydroxy-py...)
Affinity DataKi: >5.00E+3nMAssay Description:Binding affinity to mu opioid receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
Adolor

Curated by ChEMBL
LigandPNGBDBM50176364(2-(Acetyl-phenyl-amino)-N-[(S)-2-((S)-3-hydroxy-py...)
Affinity DataIC50:  300nMAssay Description:Inhibitory activity against CYP2D6More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
Adolor

Curated by ChEMBL
LigandPNGBDBM50176364(2-(Acetyl-phenyl-amino)-N-[(S)-2-((S)-3-hydroxy-py...)
Affinity DataEC50:  7.40nMAssay Description:Agonist activity at kappa opioid receptor in a [35S]GTPgammaS functional assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed