BDBM50176369 CHEMBL201884::N-((S)-2-((S)-3-hydroxypyrrolidin-1-yl)-1-phenylethyl)-N-methyl-2-(phenylamino)acetamide

SMILES CN([C@H](CN1CC[C@H](O)C1)c1ccccc1)C(=O)CNc1ccccc1

InChI Key InChIKey=JLMDSDKAMFOLIF-VQTJNVASSA-N

Data  1 KI  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50176369   

TargetKappa-type opioid receptor(Homo sapiens (Human))
Adolor

Curated by ChEMBL
LigandPNGBDBM50176369(CHEMBL201884 | N-((S)-2-((S)-3-hydroxypyrrolidin-1...)
Affinity DataKi:  0.170nMAssay Description:Binding affinity to kappa opioid receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
Adolor

Curated by ChEMBL
LigandPNGBDBM50176369(CHEMBL201884 | N-((S)-2-((S)-3-hydroxypyrrolidin-1...)
Affinity DataEC50:  0.0500nMAssay Description:Agonist activity at kappa opioid receptor in a [35S]GTPgammaS functional assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
Adolor

Curated by ChEMBL
LigandPNGBDBM50176369(CHEMBL201884 | N-((S)-2-((S)-3-hydroxypyrrolidin-1...)
Affinity DataIC50:  4.10E+3nMAssay Description:Inhibitory activity against CYP2D6More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed