BDBM50176371 CHEMBL202267::N-((S)-2-((S)-3-hydroxypyrrolidin-1-yl)-1-phenylethyl)-N-methyl-2-(4-(propylsulfonamido)phenylamino)acetamide

SMILES CCCS(=O)(=O)Nc1ccc(NCC(=O)N(C)[C@H](CN2CC[C@H](O)C2)c2ccccc2)cc1

InChI Key InChIKey=JUNLAJSELSMNNJ-XZOQPEGZSA-N

Data  1 KI  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50176371   

TargetKappa-type opioid receptor(Homo sapiens (Human))
Adolor

Curated by ChEMBL
LigandPNGBDBM50176371(CHEMBL202267 | N-((S)-2-((S)-3-hydroxypyrrolidin-1...)
Affinity DataKi:  1.5nMAssay Description:Binding affinity to kappa opioid receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
Adolor

Curated by ChEMBL
LigandPNGBDBM50176371(CHEMBL202267 | N-((S)-2-((S)-3-hydroxypyrrolidin-1...)
Affinity DataEC50:  8.30nMAssay Description:Agonist activity at kappa opioid receptor in a [35S]GTPgammaS functional assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
Adolor

Curated by ChEMBL
LigandPNGBDBM50176371(CHEMBL202267 | N-((S)-2-((S)-3-hydroxypyrrolidin-1...)
Affinity DataIC50:  9.00E+3nMAssay Description:Inhibitory activity against CYP2D6More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed