BDBM501764 4-[6-(4-aminopiperidin-1-yl)-4- [(4-methylphenyl)methyl]-5-oxo- 4,5-dihydropyrazin-2- yl]benzonitrile::US11028066, Example 2

SMILES Cc1ccc(Cn2cc(nc(N3CCC(N)CC3)c2=O)-c2ccc(cc2)C#N)cc1

InChI Key InChIKey=SUCVPAKRIWHWIX-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 501764   

TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
Celgene Quanticel Research

US Patent
LigandPNGBDBM501764(4-[6-(4-aminopiperidin-1-yl)-4- [(4-methylphenyl)...)
Affinity DataIC50: <100nMAssay Description:The enzymatic assay of LSD1 activity is based on Time Resolved-Fluorescence Resonance Energy Transfer (TR-FRET) detection. The inhibitory properties ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent