BDBM501765 4-[6-(4-aminopiperidin-1-yl)-4- [(2-fluorophenyl)methyl]-5-oxo- 4,5-dihydropyrazin-2- yl]benzonitrile::US11028066, Example 3

SMILES NC1CCN(CC1)c1nc(cn(Cc2ccccc2F)c1=O)-c1ccc(cc1)C#N

InChI Key InChIKey=PCTNBDJKANOSSV-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 501765   

TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
Celgene Quanticel Research

US Patent
LigandPNGBDBM501765(4-[6-(4-aminopiperidin-1-yl)-4- [(2-fluorophenyl)...)
Affinity DataIC50: <100nMAssay Description:The enzymatic assay of LSD1 activity is based on Time Resolved-Fluorescence Resonance Energy Transfer (TR-FRET) detection. The inhibitory properties ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent