BDBM50176833 CHEMBL224545::methyl 4-(4-methoxyphenethylamino)-1-(2-chloro-2-phenylethyl)-1H-pyrazolo[3,4-b]pyridine-5-carboxylate

SMILES COC(=O)c1cnc2n(CC(Cl)c3ccccc3)ncc2c1NCCc1ccc(OC)cc1

InChI Key InChIKey=IAZBIUQSFXFAEW-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50176833   

TargetAdenosine receptor A1(BOVINE)
Università

Curated by ChEMBL
LigandPNGBDBM50176833(CHEMBL224545 | methyl 4-(4-methoxyphenethylamino)-...)
Affinity DataKi:  6nMAssay Description:Displacement of [3H]DPCPX from adenosine A1 receptor in bovine cerebral cortical membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A1(BOVINE)
Università

Curated by ChEMBL
LigandPNGBDBM50176833(CHEMBL224545 | methyl 4-(4-methoxyphenethylamino)-...)
Affinity DataKi:  6.30nMAssay Description:Displacement of [3H]DPCPX from adenosine A1 receptor in bovine cerebral cortical membranes in absence of GTPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A1(BOVINE)
Università

Curated by ChEMBL
LigandPNGBDBM50176833(CHEMBL224545 | methyl 4-(4-methoxyphenethylamino)-...)
Affinity DataKi:  7.30nMAssay Description:Displacement of [3H]DPCPX from adenosine A1 receptor in bovine cerebral cortical membranes in presence of GTPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A1(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM50176833(CHEMBL224545 | methyl 4-(4-methoxyphenethylamino)-...)
Affinity DataKi:  94nMAssay Description:Displacement of [3H]DPCPX from human adenosine A1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed