BDBM50177279 CHEMBL436320::N-(2-(1,4-diazepan-1-yl)-4-methylquinolin-6-yl)-2-(4-(trifluoromethoxy)phenoxy)acetamide

SMILES Cc1cc(nc2ccc(NC(=O)COc3ccc(OC(F)(F)F)cc3)cc12)N1CCCNCC1

InChI Key InChIKey=MXDUTTYBWQJNKC-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50177279   

TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
7Tm Pharma

Curated by ChEMBL
LigandPNGBDBM50177279(CHEMBL436320 | N-(2-(1,4-diazepan-1-yl)-4-methylqu...)
Affinity DataIC50:  2nMAssay Description:Displacement of [125I]MCH from human MCH1 receptor expressed in CHO cell by WC assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
7Tm Pharma

Curated by ChEMBL
LigandPNGBDBM50177279(CHEMBL436320 | N-(2-(1,4-diazepan-1-yl)-4-methylqu...)
Affinity DataIC50:  12nMAssay Description:Inhibition of human MCH1 receptor by SPA assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
7Tm Pharma

Curated by ChEMBL
LigandPNGBDBM50177279(CHEMBL436320 | N-(2-(1,4-diazepan-1-yl)-4-methylqu...)
Affinity DataIC50:  71nMAssay Description:Displacement of [3H]myo-inositol from human MCH1 receptor expressed in CHO cell by IP3 assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed