BDBM50177345 1-(4-(4-(2-tert-butyl-6-(trifluoromethyl)pyrimidin-4-yl)piperazin-1-yl)butyl)-4-methylpyrimidin-2(1H)-one::CHEMBL202253

SMILES Cc1ccn(CCCCN2CCN(CC2)c2cc(nc(n2)C(C)(C)C)C(F)(F)F)c(=O)n1

InChI Key InChIKey=NZIPBDPDZPUDLD-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50177345   

TargetD(3) dopamine receptor(Homo sapiens (Human))
Abbott

Curated by ChEMBL
LigandPNGBDBM50177345(1-(4-(4-(2-tert-butyl-6-(trifluoromethyl)pyrimidin...)
Affinity DataKi:  4.40nMAssay Description:Binding affinity to cloned human dopamine D3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(3) dopamine receptor(Homo sapiens (Human))
Abbott

Curated by ChEMBL
LigandPNGBDBM50177345(1-(4-(4-(2-tert-butyl-6-(trifluoromethyl)pyrimidin...)
Affinity DataKi:  4.40nMAssay Description:Binding affinity to human cloned dopamine D3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Abbott

Curated by ChEMBL
LigandPNGBDBM50177345(1-(4-(4-(2-tert-butyl-6-(trifluoromethyl)pyrimidin...)
Affinity DataKi:  307nMAssay Description:Binding affinity to human cloned dopamine D2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Abbott

Curated by ChEMBL
LigandPNGBDBM50177345(1-(4-(4-(2-tert-butyl-6-(trifluoromethyl)pyrimidin...)
Affinity DataKi:  307nMAssay Description:Binding affinity to cloned human dopamine D2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed