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BDBM50177366 CHEMBL201110::N-(trans-4-(2-(8-methoxy-1,2,4,4a,5,6-hexahydropyrazino[1,2-a]quinolin-3-yl)ethyl)cyclohexyl)quinoline-6-carboxamide

SMILES: COc1ccc2N3CCN(CC[C@H]4CC[C@@H](CC4)NC(=O)c4ccc5ncccc5c4)CC3CCc2c1

InChI Key: InChIKey=MOCJUYFHWOGASB-JZGZJDTKSA-N

Data: 1 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50177366   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Dopamine receptor


(Rattus norvegicus (Rat))
BDBM50177366
PNG
(CHEMBL201110 | N-(trans-4-(2-(8-methoxy-1,2,4,4a,5...)
Show SMILES COc1ccc2N3CCN(CC[C@H]4CC[C@@H](CC4)NC(=O)c4ccc5ncccc5c4)CC3CCc2c1
Show InChI InChI=1S/C31H38N4O2/c1-37-28-11-13-30-24(20-28)6-10-27-21-34(17-18-35(27)30)16-14-22-4-8-26(9-5-22)33-31(36)25-7-12-29-23(19-25)3-2-15-32-29/h2-3,7,11-13,15,19-20,22,26-27H,4-6,8-10,14,16-18,21H2,1H3,(H,33,36)/t22-,26-,27?
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
9.70n/an/an/an/an/an/an/an/a



University of Michigan

Curated by ChEMBL


Assay Description
Displacement of [3H]PD 128907 from rat ventral striatal membrane dopamine D3-like receptor


Bioorg Med Chem Lett 16: 443-6 (2005)


Article DOI: 10.1016/j.bmcl.2005.09.053
BindingDB Entry DOI: 10.7270/Q2PR7VJK
More data for this
Ligand-Target Pair