BDBM501777 4-[6-(4-amino-piperidin-1-yl)-5- oxo-4-(tetrahydro-pyran-4- ylmethyl)-4,5-dihydro-pyrazin-2- yl]-2-fluoro-benzonitrile::US11028066, Example 15
SMILES NC1CCN(CC1)c1nc(cn(CC2CCOCC2)c1=O)-c1ccc(C#N)c(F)c1
InChI Key InChIKey=WFEPZORHSVKZSH-UHFFFAOYSA-N
Data 1 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 501777
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
Celgene Quanticel Research
US Patent
Celgene Quanticel Research
US Patent
Affinity DataIC50: <100nMAssay Description:The enzymatic assay of LSD1 activity is based on Time Resolved-Fluorescence Resonance Energy Transfer (TR-FRET) detection. The inhibitory properties ...More data for this Ligand-Target Pair