BDBM50178428 (S)-2-amino-3-methyl-1-(pyrrolidin-1-yl)butan-1-one::2-AMINO-3-METHYL-1-PYRROLIDIN-1-YL-BUTAN-1-ONE::CHEMBL383705

SMILES CC(C)[C@H](N)C(=O)N1CCCC1

InChI Key InChIKey=IHBAVXVTGLANPI-QMMMGPOBSA-N

Data  2 KI  12 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 14 hits for monomerid = 50178428   

TargetDipeptidyl peptidase 4(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50178428((S)-2-amino-3-methyl-1-(pyrrolidin-1-yl)butan-1-on...)
Affinity DataKi:  470nMAssay Description:Inhibition of platelet glycoprotein alpha IIb beta3 integrin in ELISAMore data for this Ligand-Target Pair
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50178428((S)-2-amino-3-methyl-1-(pyrrolidin-1-yl)butan-1-on...)
Affinity DataKi:  2.00E+3nMAssay Description:Binding affinity to DPP4More data for this Ligand-Target Pair
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50178428((S)-2-amino-3-methyl-1-(pyrrolidin-1-yl)butan-1-on...)
Affinity DataIC50:  5.40E+3nMAssay Description:Inhibition of DPP4 (unknown origin)More data for this Ligand-Target Pair
TargetDipeptidyl peptidase 8(Homo sapiens (Human))
University Of Antwerp

Curated by ChEMBL
LigandPNGBDBM50178428((S)-2-amino-3-methyl-1-(pyrrolidin-1-yl)butan-1-on...)
Affinity DataIC50:  5.20E+3nMAssay Description:Inhibition of DPP8 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 9(Homo sapiens (Human))
University Of Antwerp

Curated by ChEMBL
LigandPNGBDBM50178428((S)-2-amino-3-methyl-1-(pyrrolidin-1-yl)butan-1-on...)
Affinity DataIC50:  1.13E+4nMAssay Description:Inhibition of DPP9 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 2(Homo sapiens (Human))
University Of Warwick

Curated by ChEMBL
LigandPNGBDBM50178428((S)-2-amino-3-methyl-1-(pyrrolidin-1-yl)butan-1-on...)
Affinity DataIC50:  1.53E+5nMAssay Description:Inhibition of DPP2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50178428((S)-2-amino-3-methyl-1-(pyrrolidin-1-yl)butan-1-on...)
Affinity DataIC50:  4.00E+3nMAssay Description:In vitro inhibition of human Dipeptidylpeptidase IV.More data for this Ligand-Target Pair
TargetDipeptidyl peptidase 8(Homo sapiens (Human))
University Of Antwerp

Curated by ChEMBL
LigandPNGBDBM50178428((S)-2-amino-3-methyl-1-(pyrrolidin-1-yl)butan-1-on...)
Affinity DataIC50:  5.20E+3nMAssay Description:Inhibition of DPP8 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase IV(Porphyromonas gingivalis)
University Of Warwick

Curated by ChEMBL
LigandPNGBDBM50178428((S)-2-amino-3-methyl-1-(pyrrolidin-1-yl)butan-1-on...)
Affinity DataIC50:  2.90E+4nMAssay Description:Inhibition of Porphyromonas gingivalis N-terminal His-tagged DPP4 expressed in Escherichia coli using Gly-Pro-p-nitroanilide as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50178428((S)-2-amino-3-methyl-1-(pyrrolidin-1-yl)butan-1-on...)
Affinity DataIC50:  5.40E+3nMAssay Description:Inhibition of human DPP4More data for this Ligand-Target Pair
TargetDipeptidyl peptidase 9(Bos taurus)
University Of Warwick

Curated by ChEMBL
LigandPNGBDBM50178428((S)-2-amino-3-methyl-1-(pyrrolidin-1-yl)butan-1-on...)
Affinity DataIC50:  1.13E+4nMAssay Description:Inhibition of bovine DPP9More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 2(Homo sapiens (Human))
University Of Warwick

Curated by ChEMBL
LigandPNGBDBM50178428((S)-2-amino-3-methyl-1-(pyrrolidin-1-yl)butan-1-on...)
Affinity DataIC50:  1.53E+5nMAssay Description:Inhibition of DPP2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50178428((S)-2-amino-3-methyl-1-(pyrrolidin-1-yl)butan-1-on...)
Affinity DataIC50:  3.00E+3nMAssay Description:Inhibition of DPP4More data for this Ligand-Target Pair
TargetDipeptidyl peptidase 2(Homo sapiens (Human))
University Of Warwick

Curated by ChEMBL
LigandPNGBDBM50178428((S)-2-amino-3-methyl-1-(pyrrolidin-1-yl)butan-1-on...)
Affinity DataIC50:  2.23E+5nMAssay Description:In vitro inhibition of porcine Dipeptidylpeptidase II.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed