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BDBM50178496 7,12-dioxo-5-propoxy-7,12-dihydro-dinaphtho[1,2-b;2',3'-d]furan-6-carboxylic acid methyl ester::CHEMBL202216

SMILES: CCCOc1c(C(=O)OC)c2c3c(oc2c2ccccc12)C(=O)c1ccccc1C3=O

InChI Key: InChIKey=NHXCJEMYPNRVLD-UHFFFAOYSA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50178496   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Fibroblast growth factor receptor 1


(Homo sapiens (Human))
BDBM50178496
PNG
(7,12-dioxo-5-propoxy-7,12-dihydro-dinaphtho[1,2-b;...)
Show SMILES CCCOc1c(C(=O)OC)c2c3c(oc2c2ccccc12)C(=O)c1ccccc1C3=O
Show InChI InChI=1S/C25H18O6/c1-3-12-30-22-15-10-6-7-11-16(15)23-17(19(22)25(28)29-2)18-20(26)13-8-4-5-9-14(13)21(27)24(18)31-23/h4-11H,3,12H2,1-2H3
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a>5.00E+4n/an/an/an/an/an/a



Korea Research Institute of Chemical Technology

Curated by ChEMBL


Assay Description
Inhibitory activity against FGFR1 kinase


Bioorg Med Chem Lett 16: 737-42 (2005)


Article DOI: 10.1016/j.bmcl.2005.08.115
BindingDB Entry DOI: 10.7270/Q2SF2VQR
More data for this
Ligand-Target Pair
Epidermal growth factor receptor


(Homo sapiens (Human))
BDBM50178496
PNG
(7,12-dioxo-5-propoxy-7,12-dihydro-dinaphtho[1,2-b;...)
Show SMILES CCCOc1c(C(=O)OC)c2c3c(oc2c2ccccc12)C(=O)c1ccccc1C3=O
Show InChI InChI=1S/C25H18O6/c1-3-12-30-22-15-10-6-7-11-16(15)23-17(19(22)25(28)29-2)18-20(26)13-8-4-5-9-14(13)21(27)24(18)31-23/h4-11H,3,12H2,1-2H3
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a>5.00E+4n/an/an/an/an/an/a



Korea Research Institute of Chemical Technology

Curated by ChEMBL


Assay Description
Inhibitory activity against EGFR kinase


Bioorg Med Chem Lett 16: 737-42 (2005)


Article DOI: 10.1016/j.bmcl.2005.08.115
BindingDB Entry DOI: 10.7270/Q2SF2VQR
More data for this
Ligand-Target Pair
Platelet-derived growth factor receptor beta


(Homo sapiens (Human))
BDBM50178496
PNG
(7,12-dioxo-5-propoxy-7,12-dihydro-dinaphtho[1,2-b;...)
Show SMILES CCCOc1c(C(=O)OC)c2c3c(oc2c2ccccc12)C(=O)c1ccccc1C3=O
Show InChI InChI=1S/C25H18O6/c1-3-12-30-22-15-10-6-7-11-16(15)23-17(19(22)25(28)29-2)18-20(26)13-8-4-5-9-14(13)21(27)24(18)31-23/h4-11H,3,12H2,1-2H3
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a>5.00E+4n/an/an/an/an/an/a



Korea Research Institute of Chemical Technology

Curated by ChEMBL


Assay Description
Inhibitory activity against PDGFRbeta kinase


Bioorg Med Chem Lett 16: 737-42 (2005)


Article DOI: 10.1016/j.bmcl.2005.08.115
BindingDB Entry DOI: 10.7270/Q2SF2VQR
More data for this
Ligand-Target Pair