BDBM50179013 CHEMBL205924::moracin O
SMILES CC(C)(O)C1Cc2cc3cc(oc3cc2O1)-c1cc(O)cc(O)c1
InChI Key InChIKey=HMTMYIWMPJSCAZ-UHFFFAOYSA-N
Data 6 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 6 hits for monomerid = 50179013
TargetDual specificity protein phosphatase 3(Homo sapiens (Human))
Korea Research Institute Of Bioscience And Biotechnology (Kribb)
Curated by ChEMBL
Korea Research Institute Of Bioscience And Biotechnology (Kribb)
Curated by ChEMBL
Affinity DataIC50: >8.00E+4nMAssay Description:Inhibition of VHR DS-PTPMore data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Korea Research Institute Of Bioscience And Biotechnology (Kribb)
Curated by ChEMBL
Korea Research Institute Of Bioscience And Biotechnology (Kribb)
Curated by ChEMBL
Affinity DataIC50: >8.00E+4nMAssay Description:Inhibition of PTP1BMore data for this Ligand-Target Pair
TargetSarcoplasmic/endoplasmic reticulum calcium ATPase 1(Rattus norvegicus)
Centre Of Experimental Medicine
Curated by ChEMBL
Centre Of Experimental Medicine
Curated by ChEMBL
Affinity DataIC50: 1.11E+5nMAssay Description:Inhibition of SERCA1 in rat INS-1E cells assessed as reduction in cell viability incubated for 24 hrs by MTT assayMore data for this Ligand-Target Pair
TargetEndothelial PAS domain-containing protein 1/Hypoxia-inducible factor 1-alpha(Homo sapiens (Human))
Korean Research Institute Of Biosciences And Biotechnology
Curated by ChEMBL
Korean Research Institute Of Biosciences And Biotechnology
Curated by ChEMBL
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of hypoxia-induced HIF1 activation in human Hep3B cells by pGL3-HRE-luciferase reporter gene assayMore data for this Ligand-Target Pair
TargetHypoxia-inducible factor 1-alpha(Homo sapiens (Human))
Korean Research Institute Of Biosciences And Biotechnology
Curated by ChEMBL
Korean Research Institute Of Biosciences And Biotechnology
Curated by ChEMBL
Affinity DataIC50: 0.140nMAssay Description:Inhibition of hypoxia-induced HIF1alpha protein accumulation in human Hep3B cells treated for 30 mins measured after 12 hrs by Western blot analysisMore data for this Ligand-Target Pair
TargetHypoxia-inducible factor 1-alpha(Homo sapiens (Human))
Korean Research Institute Of Biosciences And Biotechnology
Curated by ChEMBL
Korean Research Institute Of Biosciences And Biotechnology
Curated by ChEMBL
Affinity DataIC50: 6.76nMAssay Description:Inhibition of hypoxia-induced HIF1alpha activation in human Hep3B cells after 16 hrs by HRE-luciferase reporter assayMore data for this Ligand-Target Pair