BDBM501791 4-[3-(4-ethylphenyl)-4-methyl-5- oxo-6-{[(3R)-pyrrolidin-3- ylmethyl]amino}-4,5- dihydropyrazin-2-yl]benzonitrile::US11028066, Example 29

SMILES CCc1ccc(cc1)-c1c(nc(NC[C@@H]2CCNC2)c(=O)n1C)-c1ccc(cc1)C#N

InChI Key InChIKey=GMNOJUDCMFAXPA-LJQANCHMSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 501791   

TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
Celgene Quanticel Research

US Patent
LigandPNGBDBM501791(4-[3-(4-ethylphenyl)-4-methyl-5- oxo-6-{[(3R)-pyr...)
Affinity DataIC50: <100nMAssay Description:The enzymatic assay of LSD1 activity is based on Time Resolved-Fluorescence Resonance Energy Transfer (TR-FRET) detection. The inhibitory properties ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent