BDBM501791 4-[3-(4-ethylphenyl)-4-methyl-5- oxo-6-{[(3R)-pyrrolidin-3- ylmethyl]amino}-4,5- dihydropyrazin-2-yl]benzonitrile::US11028066, Example 29
SMILES CCc1ccc(cc1)-c1c(nc(NC[C@@H]2CCNC2)c(=O)n1C)-c1ccc(cc1)C#N
InChI Key InChIKey=GMNOJUDCMFAXPA-LJQANCHMSA-N
Data 1 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 501791
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
Celgene Quanticel Research
US Patent
Celgene Quanticel Research
US Patent
Affinity DataIC50: <100nMAssay Description:The enzymatic assay of LSD1 activity is based on Time Resolved-Fluorescence Resonance Energy Transfer (TR-FRET) detection. The inhibitory properties ...More data for this Ligand-Target Pair