BDBM50179180 (1S,2R,3S,4R,5S)-4-(2-chloro-6-(cyclopentylamino)-9H-purin-9-yl)-2,3-dihydroxy-N-methylbicyclo[3.1.0]hexane-1-carboxamide::CHEMBL331291
SMILES CNC(=O)[C@]12C[C@@H]1[C@H]([C@H](O)[C@@H]2O)n1cnc2c(NC3CCCC3)nc(Cl)nc12
InChI Key InChIKey=ZXPDGTGMZKIESV-LUZJUFSVSA-N
Data 11 KI
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 11 hits for monomerid = 50179180
Affinity DataKi: 0.680nMAssay Description:Displacement of [3H]N6-R-phenylisopropyladenosine from mouse A1A adenosine receptor expressed in CHO cell membranes after 60 mins by scintillation pr...More data for this Ligand-Target Pair
Affinity DataKi: 3.5nMAssay Description:Displacement of [125I]N6-(4-amino-3-iodobenzyl)adenosine-5-N-methyluronamide from mouse A3A adenosine receptor expressed in CHO cell membranes after ...More data for this Ligand-Target Pair
TargetAdenosine receptor A3(Homo sapiens (Human))
National Institute Of Diabetes And Digestive And Kidney Diseases
Curated by ChEMBL
National Institute Of Diabetes And Digestive And Kidney Diseases
Curated by ChEMBL
Affinity DataKi: 3.70nMAssay Description:Displacement of [125I]AB-MECA from human recombinant adenosine A3 receptor expressed in CHO cells after 60 mins by liquid scintillation countingMore data for this Ligand-Target Pair
TargetAdenosine receptor A3(Homo sapiens (Human))
National Institute Of Diabetes And Digestive And Kidney Diseases
Curated by ChEMBL
National Institute Of Diabetes And Digestive And Kidney Diseases
Curated by ChEMBL
Affinity DataKi: 3.70nMAssay Description:Displacement of [125I]N6-(4-amino-3-iodobenzyl)adenosine-5-N-methyluronamide from human A3A adenosine receptor expressed in CHO cell membranes after ...More data for this Ligand-Target Pair
Affinity DataKi: 5.80nMAssay Description:Displacement of [125I]N6-(4-amino-3-iodobenzyl)adenosine-5-N-methyluronamide from rat A3A adenosine receptor expressed in CHO cell membranes after 60...More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 2B(Homo sapiens (Human))
Medical College Of Wisconsin
Curated by ChEMBL
Medical College Of Wisconsin
Curated by ChEMBL
Affinity DataKi: 12nMAssay Description:Inhibition of 5HT2B (unknown origin)More data for this Ligand-Target Pair
Affinity DataKi: 18nMAssay Description:Displacement of [3H]N6-R-phenylisopropyladenosine from human A1A adenosine receptor expressed in CHO cell membranes after 60 mins by scintillation pr...More data for this Ligand-Target Pair
Affinity DataKi: 18.3nMAssay Description:Displacement of [3H]CCPA from human recombinant adenosine A1 receptor expressed in CHO cells after 60 mins by liquid scintillation countingMore data for this Ligand-Target Pair
TargetSigma intracellular receptor 2(Homo sapiens (Human))
Medical College Of Wisconsin
Curated by ChEMBL
Medical College Of Wisconsin
Curated by ChEMBL
Affinity DataKi: 1.55E+3nMAssay Description:Inhibition of sigma receptor 2 (unknown origin)More data for this Ligand-Target Pair
TargetAdenosine receptor A2a(Homo sapiens (Human))
National Institute Of Diabetes And Digestive And Kidney Diseases
Curated by ChEMBL
National Institute Of Diabetes And Digestive And Kidney Diseases
Curated by ChEMBL
Affinity DataKi: 3.25E+3nMAssay Description:Displacement of [3H]CGS21680 from human adenosine A2A receptor expressed in HEK293 cells after 60 mins by liquid scintillation countingMore data for this Ligand-Target Pair
TargetAdenosine receptor A2a(Homo sapiens (Human))
National Institute Of Diabetes And Digestive And Kidney Diseases
Curated by ChEMBL
National Institute Of Diabetes And Digestive And Kidney Diseases
Curated by ChEMBL
Affinity DataKi: 3.25E+3nMAssay Description:Displacement of [3H]2-[p-(2-carboxyethyl)phenylethylamino]-5-N-ethylcarboxamidoadenosine from human A2A adenosine receptor expressed in HEK293 cell m...More data for this Ligand-Target Pair