BDBM50179209 (6,7-dimethoxy-2,4-dihydroindeno[1,2-c]pyrazol-3-yl)-phenyl amine::CHEMBL432219

SMILES COc1cc2Cc3c(Nc4ccccc4)[nH]nc3-c2cc1OC

InChI Key InChIKey=RWKBPANRHRUTJW-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50179209   

TargetPlatelet-derived growth factor receptor beta(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50179209((6,7-dimethoxy-2,4-dihydroindeno[1,2-c]pyrazol-3-y...)
Affinity DataIC50:  9nMAssay Description:Inhibitory activity against PDGFRbeta kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHypoxia-inducible factor 1-alpha(Homo sapiens (Human))
Gakushuin University

Curated by ChEMBL
LigandPNGBDBM50179209((6,7-dimethoxy-2,4-dihydroindeno[1,2-c]pyrazol-3-y...)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of hypoxia-induced HIF1alpha transcriptional activity in human HeLa cells expressing HRE-Luc after 12 hrs by luciferase reporter gene assa...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlatelet-derived growth factor receptor beta(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50179209((6,7-dimethoxy-2,4-dihydroindeno[1,2-c]pyrazol-3-y...)
Affinity DataIC50:  9nMAssay Description:Inhibitory activity against PDGFRbeta kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed