BDBM501795 4-{6-(4-aminopiperidin-1-yl)-3-(4- cyclopropylphenyl)-4-methyl-5- oxo-4,5-dihydropyrazin-2- yl]benzonitrile::US11028066, Example 33
SMILES Cn1c(-c2ccc(cc2)C2CC2)c(nc(N2CCC(N)CC2)c1=O)-c1ccc(cc1)C#N
InChI Key InChIKey=INIMGIFKMBOING-UHFFFAOYSA-N
Data 1 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 501795
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
Celgene Quanticel Research
US Patent
Celgene Quanticel Research
US Patent
Affinity DataIC50: <100nMAssay Description:The enzymatic assay of LSD1 activity is based on Time Resolved-Fluorescence Resonance Energy Transfer (TR-FRET) detection. The inhibitory properties ...More data for this Ligand-Target Pair