BDBM50180022 5-(4-chloro-3-methyl-phenyl)-1-(4-methyl-benzyl)-1H-pyrazole-3-carboxylic acid (1,3,3-trimethyl-bicyclo[2.2.1]hept-2-yl)-amide::CHEMBL381689

SMILES Cc1ccc(Cn2nc(cc2-c2ccc(Cl)c(C)c2)C(=O)NC2C3(C)CCC(C3)C2(C)C)cc1

InChI Key InChIKey=SUGVYNSRNKFXQM-UHFFFAOYSA-N

Data  52 KI  3 IC50  10 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 65 hits for monomerid = 50180022   

TargetCannabinoid receptor 2(MOUSE)
Uos Of Cagliari

Curated by ChEMBL
LigandPNGBDBM50180022(5-(4-chloro-3-methyl-phenyl)-1-(4-methyl-benzyl)-1...)
Affinity DataKi:  0.280nMAssay Description:Displacement of [3H]-CP-55940 from cannabinoid CB2 receptor in CD1 mouse spleen membranes after 1 hr by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 2(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50180022(5-(4-chloro-3-methyl-phenyl)-1-(4-methyl-benzyl)-1...)
Affinity DataKi:  0.280nMAssay Description:Displacement of [3H]-CP-55,940 from CB2 receptor (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 2(MOUSE)
Uos Of Cagliari

Curated by ChEMBL
LigandPNGBDBM50180022(5-(4-chloro-3-methyl-phenyl)-1-(4-methyl-benzyl)-1...)
Affinity DataKi:  0.280nMAssay Description:Displacement of [3H]CP-55940 from CD1 mouse spleen CB2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Homo sapiens (Human))
Corbus Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50180022(5-(4-chloro-3-methyl-phenyl)-1-(4-methyl-benzyl)-1...)
Affinity DataKi:  0.400nMAssay Description:Displacement of [3H]-CP-55940 from human CB1 receptor expressed in HEK293T cell membranes by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 2(Rattus norvegicus (Rat))
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50180022(5-(4-chloro-3-methyl-phenyl)-1-(4-methyl-benzyl)-1...)
Affinity DataKi:  0.600nMAssay Description:Antagonist activity at rat spleen CB2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 2(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50180022(5-(4-chloro-3-methyl-phenyl)-1-(4-methyl-benzyl)-1...)
Affinity DataKi:  0.600nMAssay Description:Displacement of [3H]CP55,940 from human recombinant CB2 receptor expressed in HEK293 cell membranes after 90 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 2(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50180022(5-(4-chloro-3-methyl-phenyl)-1-(4-methyl-benzyl)-1...)
Affinity DataKi:  0.600nMAssay Description:HEK293DHEK293iHEK293sHEK293pHEK293lHEK293aHEK293cHEK293eHEK293mHEK293eHEK293nHEK293tHEK293 HEK293oHEK293fHEK293 HEK293[HEK2933HEK293HHEK293]HEK293CHE...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 2(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50180022(5-(4-chloro-3-methyl-phenyl)-1-(4-methyl-benzyl)-1...)
Affinity DataKi:  0.600nMAssay Description:Antagonist activity at cloned human CB2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 2(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50180022(5-(4-chloro-3-methyl-phenyl)-1-(4-methyl-benzyl)-1...)
Affinity DataKi:  0.600nMAssay Description:Displacement of [3H]CP55,940 from human recombinant CB1 receptor expressed in HEK293 cell membranes after 90 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 2(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50180022(5-(4-chloro-3-methyl-phenyl)-1-(4-methyl-benzyl)-1...)
Affinity DataKi:  0.600nMAssay Description:Displacement of [3H]CP-55940 from human recombinant CB2 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 2(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50180022(5-(4-chloro-3-methyl-phenyl)-1-(4-methyl-benzyl)-1...)
Affinity DataKi:  0.600nMAssay Description:Displacement of [3H]CP-55,940 from human frontal cortex CB2 receptor expressed in CHO cell membrane after 1 hr by scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 2(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50180022(5-(4-chloro-3-methyl-phenyl)-1-(4-methyl-benzyl)-1...)
Affinity DataKi:  2.10nMAssay Description:Displacement of [3H]CP55940 from human CB2 receptor expressed in CHO cells incubated for 1 hrMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 2(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50180022(5-(4-chloro-3-methyl-phenyl)-1-(4-methyl-benzyl)-1...)
Affinity DataKi:  2.10nMAssay Description:Displacement of [3H]CP-55940 from human CB2 receptor expressed in CHO cell membranes after 1 hr by scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 2(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50180022(5-(4-chloro-3-methyl-phenyl)-1-(4-methyl-benzyl)-1...)
Affinity DataKi:  2.10nMAssay Description:Displacement of [3H]CP-55,940 from CB2 receptor (unknown origin) after 1 hr by scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 2(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50180022(5-(4-chloro-3-methyl-phenyl)-1-(4-methyl-benzyl)-1...)
Affinity DataKi:  5.40nMAssay Description:Displacement of [3H]CP-55940 from human recombinant CB2 receptor expressed in HEK cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 2(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50180022(5-(4-chloro-3-methyl-phenyl)-1-(4-methyl-benzyl)-1...)
Affinity DataKi:  5.40nMAssay Description:Displacement of [3H]CP-55940 from human recombinant CB2 receptor expressed in HEK cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 2(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50180022(5-(4-chloro-3-methyl-phenyl)-1-(4-methyl-benzyl)-1...)
Affinity DataKi:  5.40nMAssay Description:Displacement of [3H]CP-55940 from human CB2 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 2(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50180022(5-(4-chloro-3-methyl-phenyl)-1-(4-methyl-benzyl)-1...)
Affinity DataKi:  5.40nMAssay Description:Displacement of [3H]CP-55940 from human recombinant CB2 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 2(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50180022(5-(4-chloro-3-methyl-phenyl)-1-(4-methyl-benzyl)-1...)
Affinity DataKi:  5.40nMAssay Description:Displacement of [3H]CP-55940 from human recombinant CB2 receptor expressed in HEK cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 2(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50180022(5-(4-chloro-3-methyl-phenyl)-1-(4-methyl-benzyl)-1...)
Affinity DataKi:  5.40nMAssay Description:Displacement of [3H]CP 55940 from human CB2 receptor in cell free systemMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 2(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50180022(5-(4-chloro-3-methyl-phenyl)-1-(4-methyl-benzyl)-1...)
Affinity DataKi:  5.40nMAssay Description:Displacement of [3H]CP-55,940 from recombinant human CB2 receptor transfected in HEK cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 2(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50180022(5-(4-chloro-3-methyl-phenyl)-1-(4-methyl-benzyl)-1...)
Affinity DataKi:  5.40nMAssay Description:Displacement of [3H]CP-55,940 from human recombinant CB2 receptor transfected in HEK cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 2(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50180022(5-(4-chloro-3-methyl-phenyl)-1-(4-methyl-benzyl)-1...)
Affinity DataKi:  5.40nMAssay Description:Displacement of [3H]CP55940 from human recombinant CB2 receptor transfected in HEK cell membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 2(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50180022(5-(4-chloro-3-methyl-phenyl)-1-(4-methyl-benzyl)-1...)
Affinity DataKi:  5.40nMAssay Description:Displacement of [3H]CP-55940 from human CB2 receptor expressed in HEK cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 2(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50180022(5-(4-chloro-3-methyl-phenyl)-1-(4-methyl-benzyl)-1...)
Affinity DataKi:  19nMAssay Description:Displacement of [3H]-CP55940 from CB2 receptor (unknown origin) expressed in CHO cell membranes after 90 mins by liquid scintillation counting analys...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 2(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50180022(5-(4-chloro-3-methyl-phenyl)-1-(4-methyl-benzyl)-1...)
Affinity DataKi:  21nMAssay Description:Displacement of [3H]CP-55940 from human CB2 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 2(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50180022(5-(4-chloro-3-methyl-phenyl)-1-(4-methyl-benzyl)-1...)
Affinity DataKi:  21.6nMAssay Description:Displacement of [3H]CP55940 from human CB2 receptor expressed in CHO cell membranes after 1 hr by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 2(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50180022(5-(4-chloro-3-methyl-phenyl)-1-(4-methyl-benzyl)-1...)
Affinity DataKi:  51.7nMAssay Description:Displacement of [3H]CP-55940 from human CB2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 2(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50180022(5-(4-chloro-3-methyl-phenyl)-1-(4-methyl-benzyl)-1...)
Affinity DataKi:  51.7nMAssay Description:Displacement of [3H]-CP55940 from human CB2 receptor expressed in CHO cells after 1 hrMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Mus musculus (Mouse))
Uos Of Cagliari

Curated by ChEMBL
LigandPNGBDBM50180022(5-(4-chloro-3-methyl-phenyl)-1-(4-methyl-benzyl)-1...)
Affinity DataKi:  70nMAssay Description:Displacement of [3H]-CP-55940 from cannabinoid CB1 receptor in CD1 mouse brain membranes after 1 hr by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Homo sapiens (Human))
Corbus Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50180022(5-(4-chloro-3-methyl-phenyl)-1-(4-methyl-benzyl)-1...)
Affinity DataKi:  70nMAssay Description:Displacement of [3H]-CP-55,940 from CB1 receptor (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Mus musculus (Mouse))
Uos Of Cagliari

Curated by ChEMBL
LigandPNGBDBM50180022(5-(4-chloro-3-methyl-phenyl)-1-(4-methyl-benzyl)-1...)
Affinity DataKi:  70nMAssay Description:Displacement of [3H]CP-55940 from CD1 mouse brain CB1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Rattus norvegicus (rat))
Universit£

Curated by ChEMBL
LigandPNGBDBM50180022(5-(4-chloro-3-methyl-phenyl)-1-(4-methyl-benzyl)-1...)
Affinity DataKi:  400nMAssay Description:Displacement of [3H]CP-55,940 from rat brain CB1 receptor after 1 hr by scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Homo sapiens (Human))
Corbus Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50180022(5-(4-chloro-3-methyl-phenyl)-1-(4-methyl-benzyl)-1...)
Affinity DataKi:  400nMAssay Description:Displacement of [3H]CP-55,940 from human U937 cell-derived CB1 receptor expressed in CHO cell membrane after 1 hr by scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Homo sapiens (Human))
Corbus Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50180022(5-(4-chloro-3-methyl-phenyl)-1-(4-methyl-benzyl)-1...)
Affinity DataKi:  437nMAssay Description:Displacement of [3H]CP55,940 from human recombinant CB1 receptor expressed in HEK293 cell membranes after 90 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Homo sapiens (Human))
Corbus Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50180022(5-(4-chloro-3-methyl-phenyl)-1-(4-methyl-benzyl)-1...)
Affinity DataKi:  437nMAssay Description:Displacement of [3H]CP-55940 from human recombinant CB1 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Homo sapiens (Human))
Corbus Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50180022(5-(4-chloro-3-methyl-phenyl)-1-(4-methyl-benzyl)-1...)
Affinity DataKi:  437nMAssay Description:HEK293DHEK293iHEK293sHEK293pHEK293lHEK293aHEK293cHEK293eHEK293mHEK293eHEK293nHEK293tHEK293 HEK293oHEK293fHEK293 HEK293[HEK2933HEK293HHEK293]HEK293CHE...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Homo sapiens (Human))
Corbus Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50180022(5-(4-chloro-3-methyl-phenyl)-1-(4-methyl-benzyl)-1...)
Affinity DataKi:  437nMAssay Description:Displacement of [3H]CP55,940 from human recombinant CB2 receptor expressed in HEK293 cell membranes after 90 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Rattus norvegicus (rat))
Universit£

Curated by ChEMBL
LigandPNGBDBM50180022(5-(4-chloro-3-methyl-phenyl)-1-(4-methyl-benzyl)-1...)
Affinity DataKi:  437nMAssay Description:Antagonist activity at rat brain CB1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Homo sapiens (Human))
Corbus Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50180022(5-(4-chloro-3-methyl-phenyl)-1-(4-methyl-benzyl)-1...)
Affinity DataKi:  437nMAssay Description:Antagonist activity at cloned human CB1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Homo sapiens (Human))
Corbus Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50180022(5-(4-chloro-3-methyl-phenyl)-1-(4-methyl-benzyl)-1...)
Affinity DataKi: >1.00E+3nMAssay Description:Displacement of [3H]CP-55940 from human CB1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Homo sapiens (Human))
Corbus Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50180022(5-(4-chloro-3-methyl-phenyl)-1-(4-methyl-benzyl)-1...)
Affinity DataKi: >2.82E+3nMAssay Description:Displacement of [3H]CP-55940 from human recombinant CB1 receptor expressed in HEK cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Homo sapiens (Human))
Corbus Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50180022(5-(4-chloro-3-methyl-phenyl)-1-(4-methyl-benzyl)-1...)
Affinity DataKi: >2.82E+3nMAssay Description:Displacement of [3H]CP-55940 from human CB1 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Homo sapiens (Human))
Corbus Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50180022(5-(4-chloro-3-methyl-phenyl)-1-(4-methyl-benzyl)-1...)
Affinity DataKi: >2.82E+3nMAssay Description:Displacement of [3H]CP-55940 from human CB1 receptor expressed in HEK cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Homo sapiens (Human))
Corbus Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50180022(5-(4-chloro-3-methyl-phenyl)-1-(4-methyl-benzyl)-1...)
Affinity DataKi: >2.82E+3nMAssay Description:Displacement of [3H]CP-55940 from human recombinant CB1 receptor expressed in HEK cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Homo sapiens (Human))
Corbus Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50180022(5-(4-chloro-3-methyl-phenyl)-1-(4-methyl-benzyl)-1...)
Affinity DataKi: >2.82E+3nMAssay Description:Displacement of [3H]CP-55,940 from recombinant human CB1 receptor transfected in HEK cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Homo sapiens (Human))
Corbus Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50180022(5-(4-chloro-3-methyl-phenyl)-1-(4-methyl-benzyl)-1...)
Affinity DataKi: >2.82E+3nMAssay Description:Displacement of [3H]CP-55,940 from human recombinant CB1 receptor transfected in HEK cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Homo sapiens (Human))
Corbus Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50180022(5-(4-chloro-3-methyl-phenyl)-1-(4-methyl-benzyl)-1...)
Affinity DataKi: >2.82E+3nMAssay Description:Displacement of [3H]CP55940 from human recombinant CB1 receptor transfected in HEK cell membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Homo sapiens (Human))
Corbus Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50180022(5-(4-chloro-3-methyl-phenyl)-1-(4-methyl-benzyl)-1...)
Affinity DataKi:  2.89E+3nMAssay Description:Displacement of [3H]CP 55940 from human CB1 receptor in cell free systemMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Homo sapiens (Human))
Corbus Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50180022(5-(4-chloro-3-methyl-phenyl)-1-(4-methyl-benzyl)-1...)
Affinity DataKi: >5.00E+3nMAssay Description:Displacement of [3H]CP-55940 from human recombinant CB1 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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