BDBM50180786 CHEMBL436874::pGlu-His-Trp-Ser-His-D-Tyr-Leu-Arg-Pro-Gly-NH2

SMILES CC(C)C[C@H](NC(=O)CNC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](CO)NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)[C@@H](N)CCC(O)=O)C(=O)N[C@@H](CCCN=C(N)N)C(=O)N1CCC[C@H]1C(=O)NCC(O)=O

InChI Key InChIKey=HLUQDWRHBPWVNT-LVHVEONVSA-N

Data  71 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 71 hits for monomerid = 50180786   

TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50180786(CHEMBL436874 | pGlu-His-Trp-Ser-His-D-Tyr-Leu-Arg-...)
Affinity DataIC50:  4.60nMAssay Description:Displacement of [125I-His5, D-Tyr6]GnRH from mutant GnRHR, GnRHR E111AMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50180786(CHEMBL436874 | pGlu-His-Trp-Ser-His-D-Tyr-Leu-Arg-...)
Affinity DataIC50:  41.1nMAssay Description:Displacement of [125I-His5, D-Tyr6]GnRH from mutant GnRHR, GnRHR N305DMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50180786(CHEMBL436874 | pGlu-His-Trp-Ser-His-D-Tyr-Leu-Arg-...)
Affinity DataIC50:  10.3nMAssay Description:Displacement of [125I-His5, D-Tyr6]GnRH from mutant GnRHR, GnRHR W280FMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50180786(CHEMBL436874 | pGlu-His-Trp-Ser-His-D-Tyr-Leu-Arg-...)
Affinity DataIC50:  15nMAssay Description:Displacement of [125I-His5, D-Tyr6]GnRH from mutant GnRHR, GnRHR Q208EMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50180786(CHEMBL436874 | pGlu-His-Trp-Ser-His-D-Tyr-Leu-Arg-...)
Affinity DataIC50:  4.70nMAssay Description:Displacement of [125I-His5, D-Tyr6]GnRH from mutant GnRHR, GnRHR D293NMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50180786(CHEMBL436874 | pGlu-His-Trp-Ser-His-D-Tyr-Leu-Arg-...)
Affinity DataIC50:  65.1nMAssay Description:Displacement of [125I-His5, D-Tyr6]GnRH from mutant GnRHR, GnRHR F309QMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50180786(CHEMBL436874 | pGlu-His-Trp-Ser-His-D-Tyr-Leu-Arg-...)
Affinity DataIC50:  3.70nMAssay Description:Displacement of [125I-His5, D-Tyr6]GnRH from mutant GnRHR, GnRHR K191EMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50180786(CHEMBL436874 | pGlu-His-Trp-Ser-His-D-Tyr-Leu-Arg-...)
Affinity DataIC50:  3.70nMAssay Description:Displacement of [125I-His5, D-Tyr6]GnRH from mutant GnRHR, GnRHR T190KMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50180786(CHEMBL436874 | pGlu-His-Trp-Ser-His-D-Tyr-Leu-Arg-...)
Affinity DataIC50:  192nMAssay Description:Displacement of [125I-His5, D-Tyr6]GnRH from mutant GnRHR, GnRHR Y290QMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50180786(CHEMBL436874 | pGlu-His-Trp-Ser-His-D-Tyr-Leu-Arg-...)
Affinity DataIC50:  3.80nMAssay Description:Displacement of [125I-His5, D-Tyr6]GnRH from mutant GnRHR, GnRHR N27EMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50180786(CHEMBL436874 | pGlu-His-Trp-Ser-His-D-Tyr-Leu-Arg-...)
Affinity DataIC50:  5.90nMAssay Description:Displacement of [125I-His5, D-Tyr6]GnRH from mutant GnRHR, GnRHR M24AMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50180786(CHEMBL436874 | pGlu-His-Trp-Ser-His-D-Tyr-Leu-Arg-...)
Affinity DataIC50:  6.60nMAssay Description:Displacement of [125I-His5, D-Tyr6]GnRH from mutant GnRHR, GnRHR H182AMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50180786(CHEMBL436874 | pGlu-His-Trp-Ser-His-D-Tyr-Leu-Arg-...)
Affinity DataIC50:  3.10nMAssay Description:Displacement of [125I-His5, D-Tyr6]GnRH from mutant GnRHR, GnRHR S186DMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50180786(CHEMBL436874 | pGlu-His-Trp-Ser-His-D-Tyr-Leu-Arg-...)
Affinity DataIC50:  951nMAssay Description:Displacement of [125I-His5, D-Tyr6]GnRH from mutant GnRHR, GnRHR Y290LMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50180786(CHEMBL436874 | pGlu-His-Trp-Ser-His-D-Tyr-Leu-Arg-...)
Affinity DataIC50:  4.80nMAssay Description:Displacement of [125I-His5, D-Tyr6]GnRH from mutant GnRHR, GnRHR D293KMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50180786(CHEMBL436874 | pGlu-His-Trp-Ser-His-D-Tyr-Leu-Arg-...)
Affinity DataIC50:  3.30nMAssay Description:Displacement of [125I-His5, D-Tyr6]GnRH from mutant GnRHR, GnRHR S118AMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50180786(CHEMBL436874 | pGlu-His-Trp-Ser-His-D-Tyr-Leu-Arg-...)
Affinity DataIC50:  2.80nMAssay Description:Displacement of [125I-His5, D-Tyr6]GnRH from mutant GnRHR, GnRHR Y284FMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50180786(CHEMBL436874 | pGlu-His-Trp-Ser-His-D-Tyr-Leu-Arg-...)
Affinity DataIC50:  10.5nMAssay Description:Displacement of [125I-His5, D-Tyr6]GnRH from mutant GnRHR, GnRHR E111KMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50180786(CHEMBL436874 | pGlu-His-Trp-Ser-His-D-Tyr-Leu-Arg-...)
Affinity DataIC50:  6.10nMAssay Description:Displacement of [125I-His5, D-Tyr6]GnRH from mutant GnRHR, GnRHR D293EMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50180786(CHEMBL436874 | pGlu-His-Trp-Ser-His-D-Tyr-Leu-Arg-...)
Affinity DataIC50:  1.90nMAssay Description:Displacement of [125I-His5, D-Tyr6]GnRH from mutant GnRHR, GnRHR E295AMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50180786(CHEMBL436874 | pGlu-His-Trp-Ser-His-D-Tyr-Leu-Arg-...)
Affinity DataIC50:  2.40nMAssay Description:Displacement of [125I-His5, D-Tyr6]GnRH from mutant GnRHR, GnRHR E295QMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50180786(CHEMBL436874 | pGlu-His-Trp-Ser-His-D-Tyr-Leu-Arg-...)
Affinity DataIC50:  4nMAssay Description:Displacement of [125I-His5, D-Tyr6]GnRH from mutant GnRHR, GnRHR S168AMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50180786(CHEMBL436874 | pGlu-His-Trp-Ser-His-D-Tyr-Leu-Arg-...)
Affinity DataIC50:  5.60nMAssay Description:Displacement of [125I-His5, D-Tyr6]GnRH from mutant GnRHR, GnRHR F313LMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50180786(CHEMBL436874 | pGlu-His-Trp-Ser-His-D-Tyr-Leu-Arg-...)
Affinity DataIC50:  4.10nMAssay Description:Displacement of [125I-His5, D-Tyr6]GnRH from mutant GnRHR, GnRHR L117AMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50180786(CHEMBL436874 | pGlu-His-Trp-Ser-His-D-Tyr-Leu-Arg-...)
Affinity DataIC50:  3.90nMAssay Description:Displacement of [125I-His5, D-Tyr6]GnRH from mutant GnRHR, GnRHR S124AMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50180786(CHEMBL436874 | pGlu-His-Trp-Ser-His-D-Tyr-Leu-Arg-...)
Affinity DataIC50:  37.7nMAssay Description:Displacement of [125I-His5, D-Tyr6]GnRH from mutant GnRHR, GnRHR F309LMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50180786(CHEMBL436874 | pGlu-His-Trp-Ser-His-D-Tyr-Leu-Arg-...)
Affinity DataIC50:  8.10nMAssay Description:Displacement of [125I-His5, D-Tyr6]GnRH from human wild type GnRHRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50180786(CHEMBL436874 | pGlu-His-Trp-Ser-His-D-Tyr-Leu-Arg-...)
Affinity DataIC50:  48.8nMAssay Description:Displacement of [125I-His5, D-Tyr6]GnRH from mutant GnRHR, GnRHR Y290FMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50180786(CHEMBL436874 | pGlu-His-Trp-Ser-His-D-Tyr-Leu-Arg-...)
Affinity DataIC50:  5.70nMAssay Description:Displacement of [125I-His5, D-Tyr6]GnRH from mutant GnRHR, GnRHR D293AMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50180786(CHEMBL436874 | pGlu-His-Trp-Ser-His-D-Tyr-Leu-Arg-...)
Affinity DataIC50:  1.5nMAssay Description:Displacement of [125I-His5, D-Tyr6]GnRH from mutant GnRHR, GnRHR N315DMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50180786(CHEMBL436874 | pGlu-His-Trp-Ser-His-D-Tyr-Leu-Arg-...)
Affinity DataIC50:  186nMAssay Description:Displacement of [125I-His5, D-Tyr6]GnRH from mutant GnRHR, GnRHR Y284LMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50180786(CHEMBL436874 | pGlu-His-Trp-Ser-His-D-Tyr-Leu-Arg-...)
Affinity DataIC50:  18.2nMAssay Description:Displacement of [125I-His5, D-Tyr6]GnRH from mutant GnRHR, GnRHR L300AMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50180786(CHEMBL436874 | pGlu-His-Trp-Ser-His-D-Tyr-Leu-Arg-...)
Affinity DataIC50:  3.80nMAssay Description:Displacement of [125I-His5, D-Tyr6]GnRH from mutant GnRHR, GnRHR S168IMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50180786(CHEMBL436874 | pGlu-His-Trp-Ser-His-D-Tyr-Leu-Arg-...)
Affinity DataIC50:  5.80nMAssay Description:Displacement of [125I-His5, D-Tyr6]GnRH from mutant GnRHR, GnRHR N27AMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50180786(CHEMBL436874 | pGlu-His-Trp-Ser-His-D-Tyr-Leu-Arg-...)
Affinity DataIC50:  0.800nMAssay Description:Displacement of [125I-His5, D-Tyr6]GnRH from mutant GnRHR, GnRHR N315AMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50180786(CHEMBL436874 | pGlu-His-Trp-Ser-His-D-Tyr-Leu-Arg-...)
Affinity DataIC50:  3.10nMAssay Description:Displacement of [125I-His5, D-Tyr6]GnRH from mutant GnRHR, GnRHR E295KMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50180786(CHEMBL436874 | pGlu-His-Trp-Ser-His-D-Tyr-Leu-Arg-...)
Affinity DataIC50:  3.60nMAssay Description:Displacement of [125I-His5, D-Tyr6]GnRH from mutant GnRHR, GnRHR H182EMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50180786(CHEMBL436874 | pGlu-His-Trp-Ser-His-D-Tyr-Leu-Arg-...)
Affinity DataIC50:  3.60nMAssay Description:Displacement of [125I-His5, D-Tyr6]GnRH from mutant GnRHR, GnRHR A50TMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50180786(CHEMBL436874 | pGlu-His-Trp-Ser-His-D-Tyr-Leu-Arg-...)
Affinity DataIC50:  50.6nMAssay Description:Displacement of [125I-His5, D-Tyr6]GnRH from mutant GnRHR, GnRHR H306AMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50180786(CHEMBL436874 | pGlu-His-Trp-Ser-His-D-Tyr-Leu-Arg-...)
Affinity DataIC50:  8.20nMAssay Description:Displacement of [125I-His5, D-Tyr6]GnRH from mutant GnRHR, GnRHR K115QMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50180786(CHEMBL436874 | pGlu-His-Trp-Ser-His-D-Tyr-Leu-Arg-...)
Affinity DataIC50:  4.10nMAssay Description:Displacement of [125I-His5, D-Tyr6]GnRH from mutant GnRHR, GnRHR S186KMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50180786(CHEMBL436874 | pGlu-His-Trp-Ser-His-D-Tyr-Leu-Arg-...)
Affinity DataIC50:  2.40nMAssay Description:Displacement of [125I-His5, D-Tyr6]GnRH from mutant GnRHR, GnRHR Q189KMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50180786(CHEMBL436874 | pGlu-His-Trp-Ser-His-D-Tyr-Leu-Arg-...)
Affinity DataIC50:  42.2nMAssay Description:Displacement of [125I-His5, D-Tyr6]GnRH from mutant GnRHR, GnRHR D302AMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50180786(CHEMBL436874 | pGlu-His-Trp-Ser-His-D-Tyr-Leu-Arg-...)
Affinity DataIC50:  10.1nMAssay Description:Displacement of [125I-His5, D-Tyr6]GnRH from mutant GnRHR, GnRHR Q208DMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50180786(CHEMBL436874 | pGlu-His-Trp-Ser-His-D-Tyr-Leu-Arg-...)
Affinity DataIC50:  16.7nMAssay Description:Displacement of [125I-His5, D-Tyr6]GnRH from mutant GnRHR, GnRHR Q189EMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50180786(CHEMBL436874 | pGlu-His-Trp-Ser-His-D-Tyr-Leu-Arg-...)
Affinity DataIC50:  267nMAssay Description:Displacement of [125I-His5, D-Tyr6]GnRH from mutant GnRHR, GnRHR K121AMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50180786(CHEMBL436874 | pGlu-His-Trp-Ser-His-D-Tyr-Leu-Arg-...)
Affinity DataIC50:  316nMAssay Description:Displacement of [125I-His5, D-Tyr6]GnRH from mutant GnRHR, GnRHR Y283FMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50180786(CHEMBL436874 | pGlu-His-Trp-Ser-His-D-Tyr-Leu-Arg-...)
Affinity DataIC50:  66.2nMAssay Description:Displacement of [125I-His5, D-Tyr6]GnRH from mutant GnRHR, GnRHR H306KMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50180786(CHEMBL436874 | pGlu-His-Trp-Ser-His-D-Tyr-Leu-Arg-...)
Affinity DataIC50:  4.40nMAssay Description:Displacement of [125I-His5, D-Tyr6]GnRH from mutant GnRHR, GnRHR F272LMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50180786(CHEMBL436874 | pGlu-His-Trp-Ser-His-D-Tyr-Leu-Arg-...)
Affinity DataIC50:  2.70nMAssay Description:Displacement of [125I-His5, D-Tyr6]GnRH from mutant GnRHR, GnRHR L112FMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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