BDBM50180788 CHEMBL265775::pGlu-His-Trp-Ser-Tyr-Gly-Leu-Arg-Pro-Gly-NH2

SMILES CC(C)C[C@H](NC(=O)[C@@H](Cc1ccc(O)cc1)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)[C@H](CO)NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)[C@@H](N)CCC(O)=O)C(=O)N[C@@H](CCCN=C(N)N)C(=O)N1CCC[C@H]1C(=O)NCC(O)=O

InChI Key InChIKey=QWYQANIDVNALCS-KSVANVSISA-N

Data  71 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 71 hits for monomerid = 50180788   

TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50180788(CHEMBL265775 | pGlu-His-Trp-Ser-Tyr-Gly-Leu-Arg-Pr...)
Affinity DataIC50:  13.9nMAssay Description:Displacement of [125I-His5, D-Tyr6]GnRH from mutant GnRHR, GnRHR D302QMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50180788(CHEMBL265775 | pGlu-His-Trp-Ser-Tyr-Gly-Leu-Arg-Pr...)
Affinity DataIC50:  13.2nMAssay Description:Displacement of [125I-His5, D-Tyr6]GnRH from mutant GnRHR, GnRHR Y284LMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50180788(CHEMBL265775 | pGlu-His-Trp-Ser-Tyr-Gly-Leu-Arg-Pr...)
Affinity DataIC50:  1.70nMAssay Description:Displacement of [125I-His5, D-Tyr6]GnRH from mutant GnRHR, GnRHR S203KMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50180788(CHEMBL265775 | pGlu-His-Trp-Ser-Tyr-Gly-Leu-Arg-Pr...)
Affinity DataIC50:  4.10nMAssay Description:Displacement of [125I-His5, D-Tyr6]GnRH from human wild type GnRHRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50180788(CHEMBL265775 | pGlu-His-Trp-Ser-Tyr-Gly-Leu-Arg-Pr...)
Affinity DataIC50:  1.30nMAssay Description:Displacement of [125I-His5, D-Tyr6]GnRH from mutant GnRHR, GnRHR N305AMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50180788(CHEMBL265775 | pGlu-His-Trp-Ser-Tyr-Gly-Leu-Arg-Pr...)
Affinity DataIC50:  1nMAssay Description:Displacement of [125I-His5, D-Tyr6]GnRH from mutant GnRHR, GnRHR N315DMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50180788(CHEMBL265775 | pGlu-His-Trp-Ser-Tyr-Gly-Leu-Arg-Pr...)
Affinity DataIC50:  3.30nMAssay Description:Displacement of [125I-His5, D-Tyr6]GnRH from mutant GnRHR, GnRHR M24TMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50180788(CHEMBL265775 | pGlu-His-Trp-Ser-Tyr-Gly-Leu-Arg-Pr...)
Affinity DataIC50:  2.10nMAssay Description:Displacement of [125I-His5, D-Tyr6]GnRH from mutant GnRHR, GnRHR E295KMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50180788(CHEMBL265775 | pGlu-His-Trp-Ser-Tyr-Gly-Leu-Arg-Pr...)
Affinity DataIC50:  7.80nMAssay Description:Displacement of [125I-His5, D-Tyr6]GnRH from mutant GnRHR, GnRHR F309LMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50180788(CHEMBL265775 | pGlu-His-Trp-Ser-Tyr-Gly-Leu-Arg-Pr...)
Affinity DataIC50:  4.40nMAssay Description:Displacement of [125I-His5, D-Tyr6]GnRH from mutant GnRHR, GnRHR H182EMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50180788(CHEMBL265775 | pGlu-His-Trp-Ser-Tyr-Gly-Leu-Arg-Pr...)
Affinity DataIC50:  3.20nMAssay Description:Displacement of [125I-His5, D-Tyr6]GnRH from mutant GnRHR, GnRHR S168AMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50180788(CHEMBL265775 | pGlu-His-Trp-Ser-Tyr-Gly-Leu-Arg-Pr...)
Affinity DataIC50:  9.5nMAssay Description:Displacement of [125I-His5, D-Tyr6]GnRH from mutant GnRHR, GnRHR N305DMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50180788(CHEMBL265775 | pGlu-His-Trp-Ser-Tyr-Gly-Leu-Arg-Pr...)
Affinity DataIC50:  3.80nMAssay Description:Displacement of [125I-His5, D-Tyr6]GnRH from mutant GnRHR, GnRHR Q208EMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50180788(CHEMBL265775 | pGlu-His-Trp-Ser-Tyr-Gly-Leu-Arg-Pr...)
Affinity DataIC50:  50.6nMAssay Description:Displacement of [125I-His5, D-Tyr6]GnRH from mutant GnRHR, GnRHR Y283FMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50180788(CHEMBL265775 | pGlu-His-Trp-Ser-Tyr-Gly-Leu-Arg-Pr...)
Affinity DataIC50:  9.70nMAssay Description:Displacement of [125I-His5, D-Tyr6]GnRH from mutant GnRHR, GnRHR Y290QMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50180788(CHEMBL265775 | pGlu-His-Trp-Ser-Tyr-Gly-Leu-Arg-Pr...)
Affinity DataIC50:  1.80nMAssay Description:Displacement of [125I-His5, D-Tyr6]GnRH from mutant GnRHR, GnRHR L112FMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50180788(CHEMBL265775 | pGlu-His-Trp-Ser-Tyr-Gly-Leu-Arg-Pr...)
Affinity DataIC50:  8.5nMAssay Description:Displacement of [125I-His5, D-Tyr6]GnRH from mutant GnRHR, GnRHR W280FMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50180788(CHEMBL265775 | pGlu-His-Trp-Ser-Tyr-Gly-Leu-Arg-Pr...)
Affinity DataIC50:  1.30nMAssay Description:Displacement of [125I-His5, D-Tyr6]GnRH from mutant GnRHR, GnRHR M24IMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50180788(CHEMBL265775 | pGlu-His-Trp-Ser-Tyr-Gly-Leu-Arg-Pr...)
Affinity DataIC50:  5.20nMAssay Description:Displacement of [125I-His5, D-Tyr6]GnRH from mutant GnRHR, GnRHR D293KMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50180788(CHEMBL265775 | pGlu-His-Trp-Ser-Tyr-Gly-Leu-Arg-Pr...)
Affinity DataIC50:  3.30nMAssay Description:Displacement of [125I-His5, D-Tyr6]GnRH from mutant GnRHR, GnRHR E111KMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50180788(CHEMBL265775 | pGlu-His-Trp-Ser-Tyr-Gly-Leu-Arg-Pr...)
Affinity DataIC50:  3.30nMAssay Description:Displacement of [125I-His5, D-Tyr6]GnRH from mutant GnRHR, GnRHR K191EMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50180788(CHEMBL265775 | pGlu-His-Trp-Ser-Tyr-Gly-Leu-Arg-Pr...)
Affinity DataIC50:  1.70nMAssay Description:Displacement of [125I-His5, D-Tyr6]GnRH from mutant GnRHR, GnRHR Q189PMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50180788(CHEMBL265775 | pGlu-His-Trp-Ser-Tyr-Gly-Leu-Arg-Pr...)
Affinity DataIC50:  1.20nMAssay Description:Displacement of [125I-His5, D-Tyr6]GnRH from mutant GnRHR, GnRHR M24AMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50180788(CHEMBL265775 | pGlu-His-Trp-Ser-Tyr-Gly-Leu-Arg-Pr...)
Affinity DataIC50:  15.2nMAssay Description:Displacement of [125I-His5, D-Tyr6]GnRH from mutant GnRHR, GnRHR D302AMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50180788(CHEMBL265775 | pGlu-His-Trp-Ser-Tyr-Gly-Leu-Arg-Pr...)
Affinity DataIC50:  2.90nMAssay Description:Displacement of [125I-His5, D-Tyr6]GnRH from mutant GnRHR, GnRHR N27AMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50180788(CHEMBL265775 | pGlu-His-Trp-Ser-Tyr-Gly-Leu-Arg-Pr...)
Affinity DataIC50:  5.30nMAssay Description:Displacement of [125I-His5, D-Tyr6]GnRH from mutant GnRHR, GnRHR Q208DMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50180788(CHEMBL265775 | pGlu-His-Trp-Ser-Tyr-Gly-Leu-Arg-Pr...)
Affinity DataIC50:  1.90nMAssay Description:Displacement of [125I-His5, D-Tyr6]GnRH from mutant GnRHR, GnRHR Q189KMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50180788(CHEMBL265775 | pGlu-His-Trp-Ser-Tyr-Gly-Leu-Arg-Pr...)
Affinity DataIC50:  18.9nMAssay Description:Displacement of [125I-His5, D-Tyr6]GnRH from mutant GnRHR, GnRHR H306KMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50180788(CHEMBL265775 | pGlu-His-Trp-Ser-Tyr-Gly-Leu-Arg-Pr...)
Affinity DataIC50:  2.80nMAssay Description:Displacement of [125I-His5, D-Tyr6]GnRH from mutant GnRHR, GnRHR N27EMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50180788(CHEMBL265775 | pGlu-His-Trp-Ser-Tyr-Gly-Leu-Arg-Pr...)
Affinity DataIC50:  3.80nMAssay Description:Displacement of [125I-His5, D-Tyr6]GnRH from mutant GnRHR, GnRHR D293NMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50180788(CHEMBL265775 | pGlu-His-Trp-Ser-Tyr-Gly-Leu-Arg-Pr...)
Affinity DataIC50:  7.60nMAssay Description:Displacement of [125I-His5, D-Tyr6]GnRH from mutant GnRHR, GnRHR D302NMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50180788(CHEMBL265775 | pGlu-His-Trp-Ser-Tyr-Gly-Leu-Arg-Pr...)
Affinity DataIC50:  1.30nMAssay Description:Displacement of [125I-His5, D-Tyr6]GnRH from mutant GnRHR, GnRHR L300VMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50180788(CHEMBL265775 | pGlu-His-Trp-Ser-Tyr-Gly-Leu-Arg-Pr...)
Affinity DataIC50:  15.3nMAssay Description:Displacement of [125I-His5, D-Tyr6]GnRH from mutant GnRHR, GnRHR H306AMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50180788(CHEMBL265775 | pGlu-His-Trp-Ser-Tyr-Gly-Leu-Arg-Pr...)
Affinity DataIC50:  13.2nMAssay Description:Displacement of [125I-His5, D-Tyr6]GnRH from mutant GnRHR, GnRHR L300KMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50180788(CHEMBL265775 | pGlu-His-Trp-Ser-Tyr-Gly-Leu-Arg-Pr...)
Affinity DataIC50:  1.20nMAssay Description:Displacement of [125I-His5, D-Tyr6]GnRH from mutant GnRHR, GnRHR S118NMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50180788(CHEMBL265775 | pGlu-His-Trp-Ser-Tyr-Gly-Leu-Arg-Pr...)
Affinity DataIC50:  1.70nMAssay Description:Displacement of [125I-His5, D-Tyr6]GnRH from mutant GnRHR, GnRHR E295AMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50180788(CHEMBL265775 | pGlu-His-Trp-Ser-Tyr-Gly-Leu-Arg-Pr...)
Affinity DataIC50:  2nMAssay Description:Displacement of [125I-His5, D-Tyr6]GnRH from mutant GnRHR, GnRHR A50TMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50180788(CHEMBL265775 | pGlu-His-Trp-Ser-Tyr-Gly-Leu-Arg-Pr...)
Affinity DataIC50:  5.20nMAssay Description:Displacement of [125I-His5, D-Tyr6]GnRH from mutant GnRHR, GnRHR D293AMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50180788(CHEMBL265775 | pGlu-His-Trp-Ser-Tyr-Gly-Leu-Arg-Pr...)
Affinity DataIC50:  3.30nMAssay Description:Displacement of [125I-His5, D-Tyr6]GnRH from mutant GnRHR, GnRHR L117AMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50180788(CHEMBL265775 | pGlu-His-Trp-Ser-Tyr-Gly-Leu-Arg-Pr...)
Affinity DataIC50:  2.5nMAssay Description:Displacement of [125I-His5, D-Tyr6]GnRH from mutant GnRHR, GnRHR S168IMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50180788(CHEMBL265775 | pGlu-His-Trp-Ser-Tyr-Gly-Leu-Arg-Pr...)
Affinity DataIC50:  1.90nMAssay Description:Displacement of [125I-His5, D-Tyr6]GnRH from mutant GnRHR, GnRHR S203EMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50180788(CHEMBL265775 | pGlu-His-Trp-Ser-Tyr-Gly-Leu-Arg-Pr...)
Affinity DataIC50:  1.30nMAssay Description:Displacement of [125I-His5, D-Tyr6]GnRH from mutant GnRHR, GnRHR S124AMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50180788(CHEMBL265775 | pGlu-His-Trp-Ser-Tyr-Gly-Leu-Arg-Pr...)
Affinity DataIC50:  3.80nMAssay Description:Displacement of [125I-His5, D-Tyr6]GnRH from mutant GnRHR, GnRHR F313LMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50180788(CHEMBL265775 | pGlu-His-Trp-Ser-Tyr-Gly-Leu-Arg-Pr...)
Affinity DataIC50:  1.80nMAssay Description:Displacement of [125I-His5, D-Tyr6]GnRH from mutant GnRHR, GnRHR L112AMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50180788(CHEMBL265775 | pGlu-His-Trp-Ser-Tyr-Gly-Leu-Arg-Pr...)
Affinity DataIC50:  2.10nMAssay Description:Displacement of [125I-His5, D-Tyr6]GnRH from mutant GnRHR, GnRHR S186DMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50180788(CHEMBL265775 | pGlu-His-Trp-Ser-Tyr-Gly-Leu-Arg-Pr...)
Affinity DataIC50:  2.70nMAssay Description:Displacement of [125I-His5, D-Tyr6]GnRH from mutant GnRHR, GnRHR Q189AMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50180788(CHEMBL265775 | pGlu-His-Trp-Ser-Tyr-Gly-Leu-Arg-Pr...)
Affinity DataIC50:  2.10nMAssay Description:Displacement of [125I-His5, D-Tyr6]GnRH from mutant GnRHR, GnRHR E111QMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50180788(CHEMBL265775 | pGlu-His-Trp-Ser-Tyr-Gly-Leu-Arg-Pr...)
Affinity DataIC50:  4.60nMAssay Description:Displacement of [125I-His5, D-Tyr6]GnRH from mutant GnRHR, GnRHR W291FMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50180788(CHEMBL265775 | pGlu-His-Trp-Ser-Tyr-Gly-Leu-Arg-Pr...)
Affinity DataIC50:  3nMAssay Description:Displacement of [125I-His5, D-Tyr6]GnRH from mutant GnRHR, GnRHR T190KMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50180788(CHEMBL265775 | pGlu-His-Trp-Ser-Tyr-Gly-Leu-Arg-Pr...)
Affinity DataIC50:  2.40nMAssay Description:Displacement of [125I-His5, D-Tyr6]GnRH from mutant GnRHR, GnRHR F272LMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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