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BDBM50181104 CHEMBL204471::N4-benzyl-N6,2-dicyclopropyl-N4,5-dimethylpyrimidine-4,6-diamine

SMILES: CN(Cc1ccccc1)c1nc(nc(NC2CC2)c1C)C1CC1

InChI Key: InChIKey=GJVBNDHZSKKRIS-UHFFFAOYSA-N

Data: 1 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50181104   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Muscarinic acetylcholine receptor M3


(Homo sapiens (Human))
BDBM50181104
PNG
(CHEMBL204471 | N4-benzyl-N6,2-dicyclopropyl-N4,5-d...)
Show SMILES CN(Cc1ccccc1)c1nc(nc(NC2CC2)c1C)C1CC1
Show InChI InChI=1S/C19H24N4/c1-13-17(20-16-10-11-16)21-18(15-8-9-15)22-19(13)23(2)12-14-6-4-3-5-7-14/h3-7,15-16H,8-12H2,1-2H3,(H,20,21,22)
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PC cid
PC sid
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Similars

Article
PubMed
251n/an/an/an/an/an/an/an/a



UCB

Curated by ChEMBL


Assay Description
Displacement of [3H]methylscopolamine from recombinant human muscarinic M3 receptors expressed in CHO cells


Bioorg Med Chem Lett 16: 1834-9 (2006)


Article DOI: 10.1016/j.bmcl.2006.01.006
BindingDB Entry DOI: 10.7270/Q2TQ613B
More data for this
Ligand-Target Pair