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BDBM50181106 6-(azepan-1-yl)-2-cyclobutyl-N-cyclopropyl-5-methylpyrimidin-4-amine::CHEMBL205840

SMILES: Cc1c(NC2CC2)nc(nc1N1CCCCCC1)C1CCC1

InChI Key: InChIKey=QKSJHXLMFBVDOO-UHFFFAOYSA-N

Data: 1 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50181106   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Muscarinic acetylcholine receptor


(Homo sapiens (Human))
BDBM50181106
PNG
(6-(azepan-1-yl)-2-cyclobutyl-N-cyclopropyl-5-methy...)
Show SMILES Cc1c(NC2CC2)nc(nc1N1CCCCCC1)C1CCC1
Show InChI InChI=1S/C18H28N4/c1-13-16(19-15-9-10-15)20-17(14-7-6-8-14)21-18(13)22-11-4-2-3-5-12-22/h14-15H,2-12H2,1H3,(H,19,20,21)
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CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
40n/an/an/an/an/an/an/an/a



UCB

Curated by ChEMBL


Assay Description
Displacement of [3H]methylscopolamine from recombinant human muscarinic M3 receptors expressed in CHO cells


Bioorg Med Chem Lett 16: 1834-9 (2006)


Article DOI: 10.1016/j.bmcl.2006.01.006
BindingDB Entry DOI: 10.7270/Q2TQ613B
More data for this
Ligand-Target Pair