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BDBM50181114 6-(azepan-1-yl)-2-cyclopropyl-5-methyl-N-(1-methylcyclopropyl)pyrimidin-4-amine::CHEMBL208335

SMILES: Cc1c(NC2(C)CC2)nc(nc1N1CCCCCC1)C1CC1

InChI Key: InChIKey=KSCAGWNABYAOMP-UHFFFAOYSA-N

Data: 1 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50181114   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Muscarinic acetylcholine receptor M3


(Homo sapiens (Human))
BDBM50181114
PNG
(6-(azepan-1-yl)-2-cyclopropyl-5-methyl-N-(1-methyl...)
Show SMILES Cc1c(NC2(C)CC2)nc(nc1N1CCCCCC1)C1CC1
Show InChI InChI=1S/C18H28N4/c1-13-15(21-18(2)9-10-18)19-16(14-7-8-14)20-17(13)22-11-5-3-4-6-12-22/h14H,3-12H2,1-2H3,(H,19,20,21)
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PC cid
PC sid
UniChem

Similars

Article
PubMed
10n/an/an/an/an/an/an/an/a



UCB

Curated by ChEMBL


Assay Description
Displacement of [3H]methylscopolamine from recombinant human muscarinic M3 receptors expressed in CHO cells


Bioorg Med Chem Lett 16: 1834-9 (2006)


Article DOI: 10.1016/j.bmcl.2006.01.006
BindingDB Entry DOI: 10.7270/Q2TQ613B
More data for this
Ligand-Target Pair