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BDBM50181129 6-(azepan-1-yl)-N,2-dicyclopropyl-5-fluoropyrimidin-4-amine::CHEMBL206753

SMILES: Fc1c(NC2CC2)nc(nc1N1CCCCCC1)C1CC1

InChI Key: InChIKey=XLHQYBJELIZCHC-UHFFFAOYSA-N

Data: 1 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50181129   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Muscarinic acetylcholine receptor


(Homo sapiens (Human))
BDBM50181129
PNG
(6-(azepan-1-yl)-N,2-dicyclopropyl-5-fluoropyrimidi...)
Show SMILES Fc1c(NC2CC2)nc(nc1N1CCCCCC1)C1CC1
Show InChI InChI=1S/C16H23FN4/c17-13-15(18-12-7-8-12)19-14(11-5-6-11)20-16(13)21-9-3-1-2-4-10-21/h11-12H,1-10H2,(H,18,19,20)
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PC cid
PC sid
UniChem

Similars

Article
PubMed
251n/an/an/an/an/an/an/an/a



UCB

Curated by ChEMBL


Assay Description
Displacement of [3H]methylscopolamine from recombinant human muscarinic M3 receptors expressed in CHO cells


Bioorg Med Chem Lett 16: 1834-9 (2006)


Article DOI: 10.1016/j.bmcl.2006.01.006
BindingDB Entry DOI: 10.7270/Q2TQ613B
More data for this
Ligand-Target Pair