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BDBM50181131 CHEMBL427390::N,2-dicyclopropyl-5-methyl-6-(pyrrolidin-1-yl)pyrimidin-4-amine

SMILES: Cc1c(NC2CC2)nc(nc1N1CCCC1)C1CC1

InChI Key: InChIKey=FXPSOZQCBXDQGT-UHFFFAOYSA-N

Data: 1 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50181131   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Muscarinic acetylcholine receptor


(Homo sapiens (Human))
BDBM50181131
PNG
(CHEMBL427390 | N,2-dicyclopropyl-5-methyl-6-(pyrro...)
Show SMILES Cc1c(NC2CC2)nc(nc1N1CCCC1)C1CC1
Show InChI InChI=1S/C15H22N4/c1-10-13(16-12-6-7-12)17-14(11-4-5-11)18-15(10)19-8-2-3-9-19/h11-12H,2-9H2,1H3,(H,16,17,18)
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PC cid
PC sid
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Similars

Article
PubMed
100n/an/an/an/an/an/an/an/a



UCB

Curated by ChEMBL


Assay Description
Displacement of [3H]methylscopolamine from recombinant human muscarinic M3 receptors expressed in CHO cells


Bioorg Med Chem Lett 16: 1834-9 (2006)


Article DOI: 10.1016/j.bmcl.2006.01.006
BindingDB Entry DOI: 10.7270/Q2TQ613B
More data for this
Ligand-Target Pair