BDBM50182090 CHEMBL382419::tert-butyl 1-(2-hydroxy-3-(4-(3-oxo-2,3-dihydrobenzo[b][1,4]oxazin-4-yl)piperidin-1-yl)propyl)-3-(4-(trifluoromethyl)phenyl)-6,7-dihydro-1H-pyrazolo[4,3-c]pyridine-5(4H)-carboxylate

SMILES CC(C)(C)OC(=O)N1CCc2c(C1)c(nn2CC(O)CN1CCC(CC1)N1C(=O)COc2ccccc12)-c1ccc(cc1)C(F)(F)F

InChI Key InChIKey=JGSIEANYYGCVKS-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50182090   

TargetCathepsin S(Homo sapiens (Human))
Johnson And Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50182090(CHEMBL382419 | tert-butyl 1-(2-hydroxy-3-(4-(3-oxo...)
Affinity DataIC50:  826nMAssay Description:Inhibition of cathepsin SMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed