BDBM50182301 4-(4-chlorophenyl)-7-(3-fluoro-5-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)phenylthio)-2H-chromen-2-one::CHEMBL206632

SMILES OC(c1cc(F)cc(Sc2ccc3c(cc(=O)oc3c2)-c2ccc(Cl)cc2)c1)(C(F)(F)F)C(F)(F)F

InChI Key InChIKey=CDYGFQRKMFZWKB-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50182301   

TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50182301(4-(4-chlorophenyl)-7-(3-fluoro-5-(1,1,1,3,3,3-hexa...)
Affinity DataIC50:  400nMAssay Description:Inhibition of LTB4 production in calcium ionophore A23187-stimulated human whole bloodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50182301(4-(4-chlorophenyl)-7-(3-fluoro-5-(1,1,1,3,3,3-hexa...)
Affinity DataIC50:  4.30nMAssay Description:Inhibition of LTB4 production in calcium ionophore A-23187-stimulated human polymorphonuclear leukocyteMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50182301(4-(4-chlorophenyl)-7-(3-fluoro-5-(1,1,1,3,3,3-hexa...)
Affinity DataIC50:  180nMAssay Description:Inhibition of human 5-LOMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed