BDBM50182745 CHEMBL3818128

SMILES Cl.Fc1ccc(CCCCN2CCc3ccccc3C2)cc1

InChI Key InChIKey=ABCIREFWVKRPQQ-UHFFFAOYSA-N

Data  15 KI

Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 15 hits for monomerid = 50182745   

Target5-hydroxytryptamine receptor 7(Homo sapiens (Human))
Florida A&M University

Curated by ChEMBL
LigandPNGBDBM50182745(CHEMBL3818128)
Show SMILES Cl.Fc1ccc(CCCCN2CCc3ccccc3C2)cc1
Show InChI InChI=1S/C19H22FN.ClH/c20-19-10-8-16(9-11-19)5-3-4-13-21-14-12-17-6-1-2-7-18(17)15-21;/h1-2,6-11H,3-5,12-15H2;1H
Affinity DataKi:  27nMAssay Description:Displacement of [3H]LSD from human 5-HT7 receptor expressed in cell membranes after 1 hr by liquid scintillation countingMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Florida A&M University

Curated by ChEMBL
LigandPNGBDBM50182745(CHEMBL3818128)
Show SMILES Cl.Fc1ccc(CCCCN2CCc3ccccc3C2)cc1
Show InChI InChI=1S/C19H22FN.ClH/c20-19-10-8-16(9-11-19)5-3-4-13-21-14-12-17-6-1-2-7-18(17)15-21;/h1-2,6-11H,3-5,12-15H2;1H
Affinity DataKi:  141nMAssay Description:Displacement of [3H]8-OH-DPAT from human 5-HT1A receptor expressed in cell membranes after 1 hr by liquid scintillation countingMore data for this Ligand-Target Pair
TargetD(4) dopamine receptor(RAT)
Florida A&M University

Curated by ChEMBL
LigandPNGBDBM50182745(CHEMBL3818128)
Show SMILES Cl.Fc1ccc(CCCCN2CCc3ccccc3C2)cc1
Show InChI InChI=1S/C19H22FN.ClH/c20-19-10-8-16(9-11-19)5-3-4-13-21-14-12-17-6-1-2-7-18(17)15-21;/h1-2,6-11H,3-5,12-15H2;1H
Affinity DataKi:  158nMAssay Description:Displacement of [3H]N-methylspiperone from rat D4 receptor expressed in cell membranes after 1 hr by liquid scintillation countingMore data for this Ligand-Target Pair
TargetD(4) dopamine receptor(RAT)
Florida A&M University

Curated by ChEMBL
LigandPNGBDBM50182745(CHEMBL3818128)
Show SMILES Cl.Fc1ccc(CCCCN2CCc3ccccc3C2)cc1
Show InChI InChI=1S/C19H22FN.ClH/c20-19-10-8-16(9-11-19)5-3-4-13-21-14-12-17-6-1-2-7-18(17)15-21;/h1-2,6-11H,3-5,12-15H2;1H
Affinity DataKi:  160nMAssay Description:Displacement of [3H]N-methylspiperone from rat D4 receptor expressed in cell membranes after 1 hr by liquid scintillation countingMore data for this Ligand-Target Pair
TargetD(2) dopamine receptor(Homo sapiens (Human))
Florida A&M University

Curated by ChEMBL
LigandPNGBDBM50182745(CHEMBL3818128)
Show SMILES Cl.Fc1ccc(CCCCN2CCc3ccccc3C2)cc1
Show InChI InChI=1S/C19H22FN.ClH/c20-19-10-8-16(9-11-19)5-3-4-13-21-14-12-17-6-1-2-7-18(17)15-21;/h1-2,6-11H,3-5,12-15H2;1H
Affinity DataKi:  316nMAssay Description:Displacement of [3H]N-methylspiperone from human D2 receptor expressed in cell membranes after 1 hr by liquid scintillation countingMore data for this Ligand-Target Pair
TargetD(2) dopamine receptor(Homo sapiens (Human))
Florida A&M University

Curated by ChEMBL
LigandPNGBDBM50182745(CHEMBL3818128)
Show SMILES Cl.Fc1ccc(CCCCN2CCc3ccccc3C2)cc1
Show InChI InChI=1S/C19H22FN.ClH/c20-19-10-8-16(9-11-19)5-3-4-13-21-14-12-17-6-1-2-7-18(17)15-21;/h1-2,6-11H,3-5,12-15H2;1H
Affinity DataKi:  319nMAssay Description:Displacement of [3H]N-methylspiperone from human D2 receptor expressed in cell membranes after 1 hr by liquid scintillation countingMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Florida A&M University

Curated by ChEMBL
LigandPNGBDBM50182745(CHEMBL3818128)
Show SMILES Cl.Fc1ccc(CCCCN2CCc3ccccc3C2)cc1
Show InChI InChI=1S/C19H22FN.ClH/c20-19-10-8-16(9-11-19)5-3-4-13-21-14-12-17-6-1-2-7-18(17)15-21;/h1-2,6-11H,3-5,12-15H2;1H
Affinity DataKi:  726nMAssay Description:Displacement of [3H]Ketanserin from human 5-HT2A receptor expressed in cell membranes after 1 hr by liquid scintillation countingMore data for this Ligand-Target Pair
TargetHistamine H1 receptor(Homo sapiens (Human))
Florida A&M University

Curated by ChEMBL
LigandPNGBDBM50182745(CHEMBL3818128)
Show SMILES Cl.Fc1ccc(CCCCN2CCc3ccccc3C2)cc1
Show InChI InChI=1S/C19H22FN.ClH/c20-19-10-8-16(9-11-19)5-3-4-13-21-14-12-17-6-1-2-7-18(17)15-21;/h1-2,6-11H,3-5,12-15H2;1H
Affinity DataKi:  738nMAssay Description:Displacement of [3H]Pyrilamine from human H1 receptor expressed in cell membranes after 1 hr by liquid scintillation countingMore data for this Ligand-Target Pair
TargetHistamine H1 receptor(Homo sapiens (Human))
Florida A&M University

Curated by ChEMBL
LigandPNGBDBM50182745(CHEMBL3818128)
Show SMILES Cl.Fc1ccc(CCCCN2CCc3ccccc3C2)cc1
Show InChI InChI=1S/C19H22FN.ClH/c20-19-10-8-16(9-11-19)5-3-4-13-21-14-12-17-6-1-2-7-18(17)15-21;/h1-2,6-11H,3-5,12-15H2;1H
Affinity DataKi:  741nMAssay Description:Displacement of [3H]Pyrilamine from human H1 receptor expressed in cell membranes after 1 hr by liquid scintillation countingMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 2B(Homo sapiens (Human))
Florida A&M University

Curated by ChEMBL
LigandPNGBDBM50182745(CHEMBL3818128)
Show SMILES Cl.Fc1ccc(CCCCN2CCc3ccccc3C2)cc1
Show InChI InChI=1S/C19H22FN.ClH/c20-19-10-8-16(9-11-19)5-3-4-13-21-14-12-17-6-1-2-7-18(17)15-21;/h1-2,6-11H,3-5,12-15H2;1H
Affinity DataKi:  1.70E+3nMAssay Description:Displacement of [3H]LSD from human 5-HT2B receptor expressed in cell membranes after 1 hr by liquid scintillation countingMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 2B(Homo sapiens (Human))
Florida A&M University

Curated by ChEMBL
LigandPNGBDBM50182745(CHEMBL3818128)
Show SMILES Cl.Fc1ccc(CCCCN2CCc3ccccc3C2)cc1
Show InChI InChI=1S/C19H22FN.ClH/c20-19-10-8-16(9-11-19)5-3-4-13-21-14-12-17-6-1-2-7-18(17)15-21;/h1-2,6-11H,3-5,12-15H2;1H
Affinity DataKi:  1.71E+3nMAssay Description:Displacement of [3H]LSD from human 5-HT2B receptor expressed in cell membranes after 1 hr by liquid scintillation countingMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 2C(Rattus norvegicus (Rat))
Florida A&M University

Curated by ChEMBL
LigandPNGBDBM50182745(CHEMBL3818128)
Show SMILES Cl.Fc1ccc(CCCCN2CCc3ccccc3C2)cc1
Show InChI InChI=1S/C19H22FN.ClH/c20-19-10-8-16(9-11-19)5-3-4-13-21-14-12-17-6-1-2-7-18(17)15-21;/h1-2,6-11H,3-5,12-15H2;1H
Affinity DataKi:  3.98E+3nMAssay Description:Displacement of [3H]Mesulergine from rat 5-HT2C receptor expressed in cell membranes after 1 hr by liquid scintillation countingMore data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Florida A&M University

Curated by ChEMBL
LigandPNGBDBM50182745(CHEMBL3818128)
Show SMILES Cl.Fc1ccc(CCCCN2CCc3ccccc3C2)cc1
Show InChI InChI=1S/C19H22FN.ClH/c20-19-10-8-16(9-11-19)5-3-4-13-21-14-12-17-6-1-2-7-18(17)15-21;/h1-2,6-11H,3-5,12-15H2;1H
Affinity DataKi:  4.28E+3nMAssay Description:Displacement of [3H]Citalopram from human SERT expressed in cell membranes after 1 hr by liquid scintillation countingMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 2C(Rattus norvegicus (Rat))
Florida A&M University

Curated by ChEMBL
LigandPNGBDBM50182745(CHEMBL3818128)
Show SMILES Cl.Fc1ccc(CCCCN2CCc3ccccc3C2)cc1
Show InChI InChI=1S/C19H22FN.ClH/c20-19-10-8-16(9-11-19)5-3-4-13-21-14-12-17-6-1-2-7-18(17)15-21;/h1-2,6-11H,3-5,12-15H2;1H
Affinity DataKi:  4.44E+3nMAssay Description:Displacement of [3H]Mesulergine from rat 5-HT2C receptor expressed in cell membranes after 1 hr by liquid scintillation countingMore data for this Ligand-Target Pair
TargetD(3) dopamine receptor(Homo sapiens (Human))
Florida A&M University

Curated by ChEMBL
LigandPNGBDBM50182745(CHEMBL3818128)
Show SMILES Cl.Fc1ccc(CCCCN2CCc3ccccc3C2)cc1
Show InChI InChI=1S/C19H22FN.ClH/c20-19-10-8-16(9-11-19)5-3-4-13-21-14-12-17-6-1-2-7-18(17)15-21;/h1-2,6-11H,3-5,12-15H2;1H
Affinity DataKi:  6.01E+3nMAssay Description:Displacement of [3H]N-methylspiperone from human D3 receptor expressed in cell membranes after 1 hr by liquid scintillation countingMore data for this Ligand-Target Pair