BDBM50182798 (3R,4r,5S)-piperidine-3,4,5-triol::1,5-Dideoxy-1,5-imino-D-xylitol::CHEMBL110830::PIPERIDINE-3,4,5-TRIOL

SMILES O[C@H]1CNC[C@@H](O)[C@@H]1O

InChI Key InChIKey=RMCNETIHECSPMZ-SCDXWVJYSA-N

Data  4 KI  8 IC50

PDB links: 3 PDB IDs match this monomer.

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 12 hits for monomerid = 50182798   

TargetLysosomal acid glucosylceramidase(Homo sapiens (Human))
Technical University Graz

Curated by ChEMBL
LigandPNGBDBM50182798((3R,4r,5S)-piperidine-3,4,5-triol | 1,5-Dideoxy-1,...)
Affinity DataKi:  1.30E+3nMAssay Description:Inhibition of human lysosomal beta-glucocerebrosidaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysosomal acid glucosylceramidase(Homo sapiens (Human))
Technical University Graz

Curated by ChEMBL
LigandPNGBDBM50182798((3R,4r,5S)-piperidine-3,4,5-triol | 1,5-Dideoxy-1,...)
Affinity DataKi:  2.80E+3nMpH: 5.0Assay Description:Competitive inhibition of wild type human glucocerebrosidase using 2,4-dinitrophenyl beta-D-glucopyranoside as substrate after 3 mins by Dixon and Li...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-glucosidase(Agrobacterium tumefaciens)
Technical University Graz

Curated by ChEMBL
LigandPNGBDBM50182798((3R,4r,5S)-piperidine-3,4,5-triol | 1,5-Dideoxy-1,...)
Affinity DataKi:  5.00E+4nMAssay Description:Inhibition of Agrobacterium sp. beta glucosidaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-xylosidase(Thermoanaerobacter saccharolyticum)
Technische UniversitäT Graz

Curated by ChEMBL
LigandPNGBDBM50182798((3R,4r,5S)-piperidine-3,4,5-triol | 1,5-Dideoxy-1,...)
Affinity DataKi:  2.06E+5nMAssay Description:Inhibition of Thermoanaerobacterium saccharolyticum beta-xylosidaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTissue alpha-L-fucosidase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50182798((3R,4r,5S)-piperidine-3,4,5-triol | 1,5-Dideoxy-1,...)
Affinity DataIC50: >1.00E+6nMAssay Description:Compound was evaluated for inhibition of alpha-fucosidase from bovine kidney(sigma F 5884).More data for this Ligand-Target Pair
In DepthDetails Article
TargetLysosomal acid glucosylceramidase(Homo sapiens (Human))
Technical University Graz

Curated by ChEMBL
LigandPNGBDBM50182798((3R,4r,5S)-piperidine-3,4,5-triol | 1,5-Dideoxy-1,...)
Affinity DataIC50:  1.90E+3nMAssay Description:Inhibition of human GCaseMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetLysosomal acid glucosylceramidase(Homo sapiens (Human))
Technical University Graz

Curated by ChEMBL
LigandPNGBDBM50182798((3R,4r,5S)-piperidine-3,4,5-triol | 1,5-Dideoxy-1,...)
Affinity DataIC50:  2.30E+3nMAssay Description:Inhibition of human lysosomal beta-glucosidaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-galactosidase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50182798((3R,4r,5S)-piperidine-3,4,5-triol | 1,5-Dideoxy-1,...)
Affinity DataIC50:  4.00E+4nMAssay Description:Compound was evaluated for inhibition of beta-galactosidase from aspergillus oryzae (sigma G 7256).More data for this Ligand-Target Pair
In DepthDetails Article
TargetLysosomal acid glucosylceramidase(Homo sapiens (Human))
Technical University Graz

Curated by ChEMBL
LigandPNGBDBM50182798((3R,4r,5S)-piperidine-3,4,5-triol | 1,5-Dideoxy-1,...)
Affinity DataIC50:  8.80E+3nMAssay Description:Compound was evaluated for inhibition of beta-glucosidase from almonds(sigma G 4511).More data for this Ligand-Target Pair
In DepthDetails Article
Targetalpha-1,2-Mannosidase(Glycine max)
TBA

Curated by ChEMBL
LigandPNGBDBM50182798((3R,4r,5S)-piperidine-3,4,5-triol | 1,5-Dideoxy-1,...)
Affinity DataIC50:  3.60E+5nMAssay Description:Inhibition of jack bean alpha-mannosidaseMore data for this Ligand-Target Pair
In DepthDetails Article
TargetLysosomal alpha-glucosidase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50182798((3R,4r,5S)-piperidine-3,4,5-triol | 1,5-Dideoxy-1,...)
Affinity DataIC50: >1.00E+6nMAssay Description:Compound was evaluated for inhibition of alpha-glucosidase from yeast(sigma G 7256).More data for this Ligand-Target Pair
In DepthDetails Article
TargetAlpha-galactosidase A(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50182798((3R,4r,5S)-piperidine-3,4,5-triol | 1,5-Dideoxy-1,...)
Affinity DataIC50:  4.00E+4nMAssay Description:Compound was evaluated for inhibition of alpha-galactosidase from green coffee beans (sigma G 8507).More data for this Ligand-Target Pair
In DepthDetails Article