BDBM50182947 4-((S)-2-amino-3-oxo-3-((S)-3-(4-phenyl-1H-imidazol-2-yl)-3,4-dihydroisoquinolin-2(1H)-yl)propyl)benzamide::CHEMBL205388

SMILES N[C@@H](Cc1ccc(cc1)C(N)=O)C(=O)N1Cc2ccccc2C[C@H]1c1nc(c[nH]1)-c1ccccc1

InChI Key InChIKey=YAJPEEZBYVRBIB-ZCYQVOJMSA-N

Data  2 KI  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50182947   

TargetDelta-type opioid receptor(Rattus norvegicus (rat))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50182947(4-((S)-2-amino-3-oxo-3-((S)-3-(4-phenyl-1H-imidazo...)
Affinity DataKi:  1.30nMAssay Description:Displacement of [3H]DPDPE from delta opioid receptor in rat brainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50182947(4-((S)-2-amino-3-oxo-3-((S)-3-(4-phenyl-1H-imidazo...)
Affinity DataKi:  23nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor in rat brainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(MOUSE)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50182947(4-((S)-2-amino-3-oxo-3-((S)-3-(4-phenyl-1H-imidazo...)
Affinity DataEC50:  3nMAssay Description:Activity against delta opioid receptor by stimulation of [35S]GTPgammaS binding in CHO-hgamma cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(GUINEA PIG)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50182947(4-((S)-2-amino-3-oxo-3-((S)-3-(4-phenyl-1H-imidazo...)
Affinity DataEC50:  155nMAssay Description:Activity against mu opioid receptor by stimulation of [35S]GTPgammaS binding in CHO-hgamma cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed