BDBM50183276 6-(3-chloro-2-fluorobenzyl)-1-(2-hydroxyethyl)-4-oxo-1,4-dihydroquinoline-3-carboxylic acid::CHEMBL379664

SMILES OCCn1cc(C(O)=O)c(=O)c2cc(Cc3cccc(Cl)c3F)ccc12

InChI Key InChIKey=YZIAZOQBKIGPGH-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50183276   

TargetIntegrase(Human immunodeficiency virus 1)
Central Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50183276(6-(3-chloro-2-fluorobenzyl)-1-(2-hydroxyethyl)-4-o...)
Affinity DataIC50:  24nMAssay Description:Inhibition of recombinant HIV1 integrase strand transfer activityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrase(Human immunodeficiency virus 1)
University Of Southern California

Curated by ChEMBL
LigandPNGBDBM50183276(6-(3-chloro-2-fluorobenzyl)-1-(2-hydroxyethyl)-4-o...)
Affinity DataIC50:  24nMAssay Description:Inhibition of HIV1 integrase strand transfer activityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrase(Human immunodeficiency virus 1)
University Of Southern California

Curated by ChEMBL
LigandPNGBDBM50183276(6-(3-chloro-2-fluorobenzyl)-1-(2-hydroxyethyl)-4-o...)
Affinity DataIC50:  2.42E+7nMAssay Description:Inhibition of Human immunodeficiency virus 1 integrase strand transfer activityMore data for this Ligand-Target Pair
In DepthDetails Article
TargetIntegrase(Human immunodeficiency virus 1)
University Of Southern California

Curated by ChEMBL
LigandPNGBDBM50183276(6-(3-chloro-2-fluorobenzyl)-1-(2-hydroxyethyl)-4-o...)
Affinity DataIC50:  24nMAssay Description:Inhibition of HIV1 integrase DNA strand transfer activityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrase(Human immunodeficiency virus 1)
University Of Southern California

Curated by ChEMBL
LigandPNGBDBM50183276(6-(3-chloro-2-fluorobenzyl)-1-(2-hydroxyethyl)-4-o...)
Affinity DataIC50:  24nMAssay Description:Inhibition of HIV-1 integraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrase(Human immunodeficiency virus 1)
University Of Southern California

Curated by ChEMBL
LigandPNGBDBM50183276(6-(3-chloro-2-fluorobenzyl)-1-(2-hydroxyethyl)-4-o...)
Affinity DataIC50:  24nMAssay Description:Inhibition of HIV1 integrase strand transfer activityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed