BDBM501835 (S)-5-(2-(4-cyclopropylphenyl)-1- methyl-6-oxo-5-(pyrrolidin-3- ylmethylamino)-1,6- dihydropyridin-3-yl)picolinonitrile::US11028066, Example 73

SMILES Cn1c(-c2ccc(cc2)C2CC2)c(cc(NC[C@H]2CCNC2)c1=O)-c1ccc(nc1)C#N

InChI Key InChIKey=UDIGLBLDWYEWAR-KRWDZBQOSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 501835   

TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
Celgene Quanticel Research

US Patent
LigandPNGBDBM501835((S)-5-(2-(4-cyclopropylphenyl)-1- methyl-6-oxo-5-...)
Affinity DataIC50: <100nMAssay Description:The enzymatic assay of LSD1 activity is based on Time Resolved-Fluorescence Resonance Energy Transfer (TR-FRET) detection. The inhibitory properties ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent