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BDBM50184281 3-(4-fluorophenoxy)-7,8-dihydroxy-4H-chromen-4-one::CHEMBL209451

SMILES: Oc1ccc2c(occ(Oc3ccc(F)cc3)c2=O)c1O

InChI Key: InChIKey=JHQJMNSGCUBFAS-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50184281   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Heat Shock Protein 90 (Hsp90)


(Homo sapiens (human))
BDBM50184281
PNG
(3-(4-fluorophenoxy)-7,8-dihydroxy-4H-chromen-4-one...)
Show SMILES Oc1ccc2c(occ(Oc3ccc(F)cc3)c2=O)c1O
Show InChI InChI=1S/C15H9FO5/c16-8-1-3-9(4-2-8)21-12-7-20-15-10(13(12)18)5-6-11(17)14(15)19/h1-7,17,19H
PDB

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CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 3.20E+3n/an/an/an/an/an/a



The University of Kansas

Curated by ChEMBL


Assay Description
Inhibition of Hsp90 by recombinant ATPase assay


Bioorg Med Chem Lett 16: 3005-8 (2006)


Article DOI: 10.1016/j.bmcl.2006.02.063
BindingDB Entry DOI: 10.7270/Q2W37VXT
More data for this
Ligand-Target Pair