BDBM50184428 4-Chloro-3-hydroxy-7-methyl-5,6,7,8,9,14-hexahydrodibenzo[d,g]azecine::4-chloro-7-methyl-5,6,7,8,9,14-hexahydrodibenzo[d,g]azecin-3-ol::CHEMBL203637

SMILES CN1CCc2ccccc2Cc2ccc(O)c(Cl)c2CC1

InChI Key InChIKey=KRGBBAYNHOEQOO-UHFFFAOYSA-N

Data  10 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 10 hits for monomerid = 50184428   

TargetD(1B) dopamine receptor(Homo sapiens (Human))
Friedrich-Schiller-UniversitäT Jena

Curated by ChEMBL
LigandPNGBDBM50184428(4-Chloro-3-hydroxy-7-methyl-5,6,7,8,9,14-hexahydro...)
Affinity DataKi:  0.0530nMAssay Description:Inhibition of D5 dopamine receptor in HEK 293 cells by intracellular calcium assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(1B) dopamine receptor(Homo sapiens (Human))
Friedrich-Schiller-UniversitäT Jena

Curated by ChEMBL
LigandPNGBDBM50184428(4-Chloro-3-hydroxy-7-methyl-5,6,7,8,9,14-hexahydro...)
Affinity DataKi:  0.0570nMAssay Description:Binding affinity to D5 dopamine receptor by radioligand binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(1A) dopamine receptor(Homo sapiens (Human))
Friedrich-Schiller-UniversitäT Jena

Curated by ChEMBL
LigandPNGBDBM50184428(4-Chloro-3-hydroxy-7-methyl-5,6,7,8,9,14-hexahydro...)
Affinity DataKi:  0.460nMAssay Description:Inhibition of D1 dopamine receptor in HEK 293 cells by intracellular calcium assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(1A) dopamine receptor(Homo sapiens (Human))
Friedrich-Schiller-UniversitäT Jena

Curated by ChEMBL
LigandPNGBDBM50184428(4-Chloro-3-hydroxy-7-methyl-5,6,7,8,9,14-hexahydro...)
Affinity DataKi:  0.813nMAssay Description:Displacement of [3H]SCH23390 from human cloned dopamine D1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(1A) dopamine receptor(Homo sapiens (Human))
Friedrich-Schiller-UniversitäT Jena

Curated by ChEMBL
LigandPNGBDBM50184428(4-Chloro-3-hydroxy-7-methyl-5,6,7,8,9,14-hexahydro...)
Affinity DataKi:  0.830nMAssay Description:Displacement of [3H]SCH 23390 from D1 dopamine receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Friedrich-Schiller-Universit£T Jena

Curated by ChEMBL
LigandPNGBDBM50184428(4-Chloro-3-hydroxy-7-methyl-5,6,7,8,9,14-hexahydro...)
Affinity DataKi:  3.55nMAssay Description:Displacement of [3H]SCH23390 from human cloned dopamine D2L receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Friedrich-Schiller-Universit£T Jena

Curated by ChEMBL
LigandPNGBDBM50184428(4-Chloro-3-hydroxy-7-methyl-5,6,7,8,9,14-hexahydro...)
Affinity DataKi:  4nMAssay Description:Displacement of [3H]spiperone from D2L dopamine receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Friedrich-Schiller-Universit£T Jena

Curated by ChEMBL
LigandPNGBDBM50184428(4-Chloro-3-hydroxy-7-methyl-5,6,7,8,9,14-hexahydro...)
Affinity DataKi:  6.10nMAssay Description:Inhibition of D2L dopamine receptor in HEK 293 cells by intracellular calcium assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(4) dopamine receptor(Homo sapiens (Human))
Friedrich-Schiller-UniversitäT Jena

Curated by ChEMBL
LigandPNGBDBM50184428(4-Chloro-3-hydroxy-7-methyl-5,6,7,8,9,14-hexahydro...)
Affinity DataKi:  18.7nMAssay Description:Binding affinity to D4 dopamine receptor by radioligand binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(3) dopamine receptor(Homo sapiens (Human))
Friedrich-Schiller-UniversitäT Jena

Curated by ChEMBL
LigandPNGBDBM50184428(4-Chloro-3-hydroxy-7-methyl-5,6,7,8,9,14-hexahydro...)
Affinity DataKi:  24.6nMAssay Description:Binding affinity to D3 dopamine receptor by radioligand binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed