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BDBM50184802 4-phenyl-1-((1-phenyl-1H-1,2,3-triazol-4-yl)methyl)-1,2,3,6-tetrahydropyridine::CHEMBL379177

SMILES: C(N1CCC(=CC1)c1ccccc1)c1cn(nn1)-c1ccccc1

InChI Key: InChIKey=VEDCYFFCKNISSG-UHFFFAOYSA-N

Data: 5 KI

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50184802   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
D(4) dopamine receptor


(Homo sapiens (Human))
BDBM50184802
PNG
(4-phenyl-1-((1-phenyl-1H-1,2,3-triazol-4-yl)methyl...)
Show SMILES C(N1CCC(=CC1)c1ccccc1)c1cn(nn1)-c1ccccc1
Show InChI InChI=1S/C20H20N4/c1-3-7-17(8-4-1)18-11-13-23(14-12-18)15-19-16-24(22-21-19)20-9-5-2-6-10-20/h1-11,16H,12-15H2
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PC sid
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3.20n/an/an/an/an/an/an/an/a



Friedrich-Alexander University

Curated by ChEMBL


Assay Description
Displacement of [3H]spiperone from human cloned dopamine D4 receptor expressed in CHO cells


Bioorg Med Chem Lett 16: 2955-9 (2006)


Article DOI: 10.1016/j.bmcl.2006.02.075
BindingDB Entry DOI: 10.7270/Q21N80QX
More data for this
Ligand-Target Pair
D(3) dopamine receptor


(Homo sapiens (Human))
BDBM50184802
PNG
(4-phenyl-1-((1-phenyl-1H-1,2,3-triazol-4-yl)methyl...)
Show SMILES C(N1CCC(=CC1)c1ccccc1)c1cn(nn1)-c1ccccc1
Show InChI InChI=1S/C20H20N4/c1-3-7-17(8-4-1)18-11-13-23(14-12-18)15-19-16-24(22-21-19)20-9-5-2-6-10-20/h1-11,16H,12-15H2
PDB

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antibodypedia
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UniChem
Article
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94n/an/an/an/an/an/an/an/a



Friedrich-Alexander University

Curated by ChEMBL


Assay Description
Displacement of [3H]spiperone from human cloned dopamine D3 receptor expressed in CHO cells


Bioorg Med Chem Lett 16: 2955-9 (2006)


Article DOI: 10.1016/j.bmcl.2006.02.075
BindingDB Entry DOI: 10.7270/Q21N80QX
More data for this
Ligand-Target Pair
D(2) dopamine receptor


(Homo sapiens (Human))
BDBM50184802
PNG
(4-phenyl-1-((1-phenyl-1H-1,2,3-triazol-4-yl)methyl...)
Show SMILES C(N1CCC(=CC1)c1ccccc1)c1cn(nn1)-c1ccccc1
Show InChI InChI=1S/C20H20N4/c1-3-7-17(8-4-1)18-11-13-23(14-12-18)15-19-16-24(22-21-19)20-9-5-2-6-10-20/h1-11,16H,12-15H2
PDB

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110n/an/an/an/an/an/an/an/a



Friedrich-Alexander University

Curated by ChEMBL


Assay Description
Displacement of [3H]spiperone from human cloned dopamine D2(short) receptor expressed in CHO cells


Bioorg Med Chem Lett 16: 2955-9 (2006)


Article DOI: 10.1016/j.bmcl.2006.02.075
BindingDB Entry DOI: 10.7270/Q21N80QX
More data for this
Ligand-Target Pair
D(2) dopamine receptor


(Homo sapiens (Human))
BDBM50184802
PNG
(4-phenyl-1-((1-phenyl-1H-1,2,3-triazol-4-yl)methyl...)
Show SMILES C(N1CCC(=CC1)c1ccccc1)c1cn(nn1)-c1ccccc1
Show InChI InChI=1S/C20H20N4/c1-3-7-17(8-4-1)18-11-13-23(14-12-18)15-19-16-24(22-21-19)20-9-5-2-6-10-20/h1-11,16H,12-15H2
PDB

Reactome pathway
KEGG

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220n/an/an/an/an/an/an/an/a



Friedrich-Alexander University

Curated by ChEMBL


Assay Description
Displacement of [3H]spiperone from human cloned dopamine D2(long) receptor expressed in CHO cells


Bioorg Med Chem Lett 16: 2955-9 (2006)


Article DOI: 10.1016/j.bmcl.2006.02.075
BindingDB Entry DOI: 10.7270/Q21N80QX
More data for this
Ligand-Target Pair
Dopamine D1 receptor


(Sus scrofa)
BDBM50184802
PNG
(4-phenyl-1-((1-phenyl-1H-1,2,3-triazol-4-yl)methyl...)
Show SMILES C(N1CCC(=CC1)c1ccccc1)c1cn(nn1)-c1ccccc1
Show InChI InChI=1S/C20H20N4/c1-3-7-17(8-4-1)18-11-13-23(14-12-18)15-19-16-24(22-21-19)20-9-5-2-6-10-20/h1-11,16H,12-15H2
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
1.00E+4n/an/an/an/an/an/an/an/a



Friedrich-Alexander University

Curated by ChEMBL


Assay Description
Displacement of [3H]SCH23390 from dopamine D1 receptor in porcine striatal membrane


Bioorg Med Chem Lett 16: 2955-9 (2006)


Article DOI: 10.1016/j.bmcl.2006.02.075
BindingDB Entry DOI: 10.7270/Q21N80QX
More data for this
Ligand-Target Pair