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BDBM50185111 2-(3,4-dimethoxybenzamido)-5,6-dihydro-4H-cyclopenta[b]thiophene-3-carboxamide::CHEMBL210601

SMILES: COc1ccc(cc1OC)C(=O)Nc1sc2CCCc2c1C(N)=O

InChI Key: InChIKey=KSKKTEOMELLSQN-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50185111   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Tyrosine-protein kinase receptor FLT3


(Homo sapiens (Human))
BDBM50185111
PNG
(2-(3,4-dimethoxybenzamido)-5,6-dihydro-4H-cyclopen...)
Show SMILES COc1ccc(cc1OC)C(=O)Nc1sc2CCCc2c1C(N)=O
Show InChI InChI=1S/C17H18N2O4S/c1-22-11-7-6-9(8-12(11)23-2)16(21)19-17-14(15(18)20)10-4-3-5-13(10)24-17/h6-8H,3-5H2,1-2H3,(H2,18,20)(H,19,21)
PDB
MMDB

KEGG

UniProtKB/SwissProt

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CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 27n/an/an/an/an/an/a



Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL


Assay Description
Inhibition of FLT3


Bioorg Med Chem Lett 16: 3282-6 (2006)


Article DOI: 10.1016/j.bmcl.2006.03.032
BindingDB Entry DOI: 10.7270/Q2R49QCV
More data for this
Ligand-Target Pair