BDBM50185353 3-tert-butyl-1-(3-(4-octylphenoxy)-2-oxopropyl)-1H-indole-5-carboxylic acid::3-tert-butyl-1-[3-(4-octylphenoxy)-2-oxopropyl]indole-5-carboxylic acid::CHEMBL206943

SMILES CCCCCCCCc1ccc(OCC(=O)Cn2cc(c3cc(ccc23)C(O)=O)C(C)(C)C)cc1

InChI Key InChIKey=YOFIHHQLZJBRDF-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50185353   

TargetCytosolic phospholipase A2(Homo sapiens (Human))
University Of MüNster

Curated by ChEMBL
LigandPNGBDBM50185353(3-tert-butyl-1-(3-(4-octylphenoxy)-2-oxopropyl)-1H...)
Affinity DataIC50:  3.30E+3nMAssay Description:Inhibition of cPLA2alpha activity assessed by A23187-induced arachidonic acid release in human plateletMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytosolic phospholipase A2(Homo sapiens (Human))
University Of MüNster

Curated by ChEMBL
LigandPNGBDBM50185353(3-tert-butyl-1-(3-(4-octylphenoxy)-2-oxopropyl)-1H...)
Affinity DataIC50:  340nMAssay Description:Inhibition of cPLA2 from human platelets by RP-HPLCMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytosolic phospholipase A2(Homo sapiens (Human))
University Of MüNster

Curated by ChEMBL
LigandPNGBDBM50185353(3-tert-butyl-1-(3-(4-octylphenoxy)-2-oxopropyl)-1H...)
Affinity DataIC50:  230nMAssay Description:Inhibition of cPLA2-alpha activity assessed by TPA-induced arachidonic acid release in human plateletMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytosolic phospholipase A2(Homo sapiens (Human))
University Of MüNster

Curated by ChEMBL
LigandPNGBDBM50185353(3-tert-butyl-1-(3-(4-octylphenoxy)-2-oxopropyl)-1H...)
Affinity DataIC50:  340nMAssay Description:Inhibition of human isolated cPLA2alpha by vescicle assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed