BDBM50185776 4-(2,4-difluorophenethyl)-1-(4-fluorophenylsulfonyl)piperidin-4-ol::CHEMBL382146

SMILES OC1(CCc2ccc(F)cc2F)CCN(CC1)S(=O)(=O)c1ccc(F)cc1

InChI Key InChIKey=XWWMSPYJKMBSOT-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50185776   

Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Merck Sharp & Dohme

Curated by ChEMBL
LigandPNGBDBM50185776(4-(2,4-difluorophenethyl)-1-(4-fluorophenylsulfony...)
Affinity DataKi:  190nMAssay Description:Binding affinity to human 5HT2AMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Merck Sharp & Dohme

Curated by ChEMBL
LigandPNGBDBM50185776(4-(2,4-difluorophenethyl)-1-(4-fluorophenylsulfony...)
Affinity DataKi: >1.00E+3nMAssay Description:Binding affinity to human D2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
Merck Sharp & Dohme

Curated by ChEMBL
LigandPNGBDBM50185776(4-(2,4-difluorophenethyl)-1-(4-fluorophenylsulfony...)
Affinity DataKi: >4.00E+3nMAssay Description:Binding affinity to human 5HT2CMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Merck Sharp & Dohme

Curated by ChEMBL
LigandPNGBDBM50185776(4-(2,4-difluorophenethyl)-1-(4-fluorophenylsulfony...)
Affinity DataKi: >9.00E+3nMAssay Description:Binding affinity to human IKrMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed