BDBM50186088 (S)-2-amino-N-((S)-2-(biphenyl-4-yl)-1-cyanoethyl)butanamide::(S)-2-amino-N-((S)-2-biphenyl-4-yl-1-cyano-ethyl)-butyramide::CHEMBL212521
SMILES CC[C@H](N)C(=O)N[C@@H](Cc1ccc(cc1)-c1ccccc1)C#N
InChI Key InChIKey=DPOJEFZKFIWUGN-ROUUACIJSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 17 hits for monomerid = 50186088
TargetCathepsin B(Homo sapiens (Human))
Genomics Institute Of The Novartis Research Foundation
Curated by ChEMBL
Genomics Institute Of The Novartis Research Foundation
Curated by ChEMBL
Affinity DataKi: >10nMAssay Description:Inhibition of human recombinant cathepsin B by fluorescence assayMore data for this Ligand-Target Pair
TargetCathepsin S(Homo sapiens (Human))
Genomics Institute Of The Novartis Research Foundation
Curated by ChEMBL
Genomics Institute Of The Novartis Research Foundation
Curated by ChEMBL
Affinity DataKi: >10nMAssay Description:Inhibition of human recombinant cathepsin S by fluorescence assayMore data for this Ligand-Target Pair
TargetPro-cathepsin H(Homo sapiens (Human))
Genomics Institute Of The Novartis Research Foundation
Curated by ChEMBL
Genomics Institute Of The Novartis Research Foundation
Curated by ChEMBL
Affinity DataKi: 3.70E+3nMAssay Description:Inhibition of human recombinant cathepsin H by fluorescence assayMore data for this Ligand-Target Pair
TargetCathepsin K(Homo sapiens (Human))
Genomics Institute Of The Novartis Research Foundation
Curated by ChEMBL
Genomics Institute Of The Novartis Research Foundation
Curated by ChEMBL
Affinity DataKi: 1.80E+4nMAssay Description:Inhibition of human recombinant cathepsin K by fluorescence assayMore data for this Ligand-Target Pair
TargetDipeptidyl peptidase 1(Homo sapiens (Human))
Genomics Institute Of The Novartis Research Foundation
Curated by ChEMBL
Genomics Institute Of The Novartis Research Foundation
Curated by ChEMBL
Affinity DataIC50: 6.10E+3nMAssay Description:Inhibition of cathepsin C in human B721 cells by FACS assayMore data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of Cathepsin LMore data for this Ligand-Target Pair
Affinity DataIC50: 1.26E+4nMAssay Description:Inhibition of CYP2D6More data for this Ligand-Target Pair
TargetCathepsin B(Homo sapiens (Human))
Genomics Institute Of The Novartis Research Foundation
Curated by ChEMBL
Genomics Institute Of The Novartis Research Foundation
Curated by ChEMBL
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of Cathepsin BMore data for this Ligand-Target Pair
Affinity DataIC50: >2.00E+4nMAssay Description:Inhibition of CYP2C19More data for this Ligand-Target Pair
Affinity DataIC50: 3.60E+3nMAssay Description:Inhibition of CYP3A4More data for this Ligand-Target Pair
Affinity DataIC50: >2.00E+4nMAssay Description:Inhibition of CYP2C9More data for this Ligand-Target Pair
Affinity DataIC50: 1.49E+4nMAssay Description:Inhibition of CYP1A2More data for this Ligand-Target Pair
TargetDipeptidyl peptidase 1(Homo sapiens (Human))
Genomics Institute Of The Novartis Research Foundation
Curated by ChEMBL
Genomics Institute Of The Novartis Research Foundation
Curated by ChEMBL
Affinity DataIC50: 1.00E+4nMAssay Description:Blockade of conjugation of cathepsin C in human B721 cells to I125-labeled (S)-2-amino-N-((S)-1-(4-hydroxy-3-iodophenylsulfonyl)-5-phenylpent-1-en-3-...More data for this Ligand-Target Pair
TargetPro-cathepsin H(Homo sapiens (Human))
Genomics Institute Of The Novartis Research Foundation
Curated by ChEMBL
Genomics Institute Of The Novartis Research Foundation
Curated by ChEMBL
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of Cathepsin HMore data for this Ligand-Target Pair
TargetDipeptidyl peptidase 1(Homo sapiens (Human))
Genomics Institute Of The Novartis Research Foundation
Curated by ChEMBL
Genomics Institute Of The Novartis Research Foundation
Curated by ChEMBL
Affinity DataIC50: 13nMAssay Description:Inhibition of human DPP1More data for this Ligand-Target Pair
TargetDipeptidyl peptidase 1(Homo sapiens (Human))
Genomics Institute Of The Novartis Research Foundation
Curated by ChEMBL
Genomics Institute Of The Novartis Research Foundation
Curated by ChEMBL
Affinity DataIC50: 2nMAssay Description:Inhibition of recombinant human cathepsin C using H-Gly-Arg-AMC as substrate preincubated for 30 mins before substrate addition measured after 60 min...More data for this Ligand-Target Pair
TargetDipeptidyl peptidase 1(Homo sapiens (Human))
Genomics Institute Of The Novartis Research Foundation
Curated by ChEMBL
Genomics Institute Of The Novartis Research Foundation
Curated by ChEMBL
Affinity DataIC50: 63nMAssay Description:Inhibition of cathepsin C in human THP1 cells assessed as inhibition of H-Gly-Phe-AFC cleavage by fluorescence assayMore data for this Ligand-Target Pair