BDBM50186434 (R)-methyl 2-(3-(4-hydroxyphenyl)-4,5-dihydroisoxazol-5-yl)acetate::3-(4-HYDROXYPHENYL)-4,5-DIHYDRO-5-ISOXAZOLE-ACETIC ACID METHYL ESTER::CHEMBL211769

SMILES COC(=O)C[C@H]1CC(=NO1)c1ccc(O)cc1

InChI Key InChIKey=AIXMJTYHQHQJLU-SNVBAGLBSA-N

Data  3 IC50

PDB links: 1 PDB ID matches this monomer.

Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50186434   

TargetMacrophage migration inhibitory factor(Homo sapiens (Human))
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50186434((R)-methyl 2-(3-(4-hydroxyphenyl)-4,5-dihydroisoxa...)
Show SMILES COC(=O)C[C@H]1CC(=NO1)c1ccc(O)cc1
Show InChI InChI=1S/C12H13NO4/c1-16-12(15)7-10-6-11(13-17-10)8-2-4-9(14)5-3-8/h2-5,10,14H,6-7H2,1H3/t10-/m1/s1
Affinity DataIC50: 1.44E+4nMAssay Description:Inhibition of recombinant human MIF tautomerase activity expressed in Escherichia coli using L-dopachrome methyl ester as substrate incubated for 30 ...More data for this Ligand-Target Pair
TargetMacrophage migration inhibitory factor(Homo sapiens (Human))
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50186434((R)-methyl 2-(3-(4-hydroxyphenyl)-4,5-dihydroisoxa...)
Show SMILES COC(=O)C[C@H]1CC(=NO1)c1ccc(O)cc1
Show InChI InChI=1S/C12H13NO4/c1-16-12(15)7-10-6-11(13-17-10)8-2-4-9(14)5-3-8/h2-5,10,14H,6-7H2,1H3/t10-/m1/s1
Affinity DataIC50: 7.00E+3nMAssay Description:Inhibition of human recombinant MIF tautomeraseMore data for this Ligand-Target Pair
TargetMacrophage migration inhibitory factor(Homo sapiens (Human))
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50186434((R)-methyl 2-(3-(4-hydroxyphenyl)-4,5-dihydroisoxa...)
Show SMILES COC(=O)C[C@H]1CC(=NO1)c1ccc(O)cc1
Show InChI InChI=1S/C12H13NO4/c1-16-12(15)7-10-6-11(13-17-10)8-2-4-9(14)5-3-8/h2-5,10,14H,6-7H2,1H3/t10-/m1/s1
Affinity DataIC50: 7.00E+3nMAssay Description:Inhibition of MIF tautomerase activityMore data for this Ligand-Target Pair