BDBM50187063 CHEMBL379386::GNF-PF-2722::N2-(4-bromophenyl)-N4-(furan-2-ylmethyl)quinazoline-2,4-diamine
SMILES Brc1ccc(Nc2nc(NCc3ccco3)c3ccccc3n2)cc1
InChI Key InChIKey=WYDGHRZFSRBHSA-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 50187063
TargetSon of sevenless homolog 1(Homo sapiens (Human))
Vanderbilt University School Of Medicine
Curated by ChEMBL
Vanderbilt University School Of Medicine
Curated by ChEMBL
Affinity DataEC50: >1.00E+5nMAssay Description:Activation of SOS1 in human HeLa cells assessed as increase in RAS-GTP levels after 30 mins by pull-down assayMore data for this Ligand-Target Pair
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Mus musculus)
Research Center Idrtech
Curated by ChEMBL
Research Center Idrtech
Curated by ChEMBL
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of mouse Dyrk1A autophosphorylation in HEk293 cellsMore data for this Ligand-Target Pair