BDBM50187132 3,5-Dimethoxy-4-hydroxybenzoic acid::4-hydroxy-3,5-dimethoxybenzoic acid::CHEMBL1414::Syringic acid

SMILES COc1cc(cc(OC)c1O)C(O)=O

InChI Key InChIKey=JMSVCTWVEWCHDZ-UHFFFAOYSA-N

Data  14 KI  3 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 17 hits for monomerid = 50187132   

TargetCarbonic anhydrase 2(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50187132(3,5-Dimethoxy-4-hydroxybenzoic acid | 4-hydroxy-3,...)
Affinity DataKi:  3.19E+3nMAssay Description:Inhibition of human CA2 by stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 1(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50187132(3,5-Dimethoxy-4-hydroxybenzoic acid | 4-hydroxy-3,...)
Affinity DataKi:  4.15E+3nMAssay Description:Inhibition of human CA1 by stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 5A, mitochondrial(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50187132(3,5-Dimethoxy-4-hydroxybenzoic acid | 4-hydroxy-3,...)
Affinity DataKi:  6.34E+3nMAssay Description:Inhibition of human CA5A by stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 6(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50187132(3,5-Dimethoxy-4-hydroxybenzoic acid | 4-hydroxy-3,...)
Affinity DataKi:  7.55E+3nMAssay Description:Inhibition of human CA6 by stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 7(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50187132(3,5-Dimethoxy-4-hydroxybenzoic acid | 4-hydroxy-3,...)
Affinity DataKi:  7.81E+3nMAssay Description:Inhibition of human CA7 by stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 9(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50187132(3,5-Dimethoxy-4-hydroxybenzoic acid | 4-hydroxy-3,...)
Affinity DataKi:  8.20E+3nMAssay Description:Inhibition of human CA9 by stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 3(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50187132(3,5-Dimethoxy-4-hydroxybenzoic acid | 4-hydroxy-3,...)
Affinity DataKi:  8.58E+3nMAssay Description:Inhibition of human CA3 by stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 12(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50187132(3,5-Dimethoxy-4-hydroxybenzoic acid | 4-hydroxy-3,...)
Affinity DataKi:  9.01E+3nMAssay Description:Inhibition of human CA12 by stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 14(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50187132(3,5-Dimethoxy-4-hydroxybenzoic acid | 4-hydroxy-3,...)
Affinity DataKi:  9.14E+3nMAssay Description:Inhibition of human CA14 by stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 4(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50187132(3,5-Dimethoxy-4-hydroxybenzoic acid | 4-hydroxy-3,...)
Affinity DataKi:  1.06E+4nMAssay Description:Inhibition of human CA4 by stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 13(Mus musculus (mouse))
Universit£

Curated by ChEMBL
LigandPNGBDBM50187132(3,5-Dimethoxy-4-hydroxybenzoic acid | 4-hydroxy-3,...)
Affinity DataKi:  1.10E+4nMAssay Description:Inhibition of mouse CA13 by stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 5B, mitochondrial(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50187132(3,5-Dimethoxy-4-hydroxybenzoic acid | 4-hydroxy-3,...)
Affinity DataKi:  3.54E+4nMAssay Description:Inhibition of human CA5B by stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50187132(3,5-Dimethoxy-4-hydroxybenzoic acid | 4-hydroxy-3,...)
Affinity DataKi:  6.95E+5nM ΔG°:  -4.31kcal/molepH: 7.4 T: 2°CAssay Description:Carbonic anhydrase activity was assayed by following the change in absorbance at 348 nm of 4-nitrophenylacetate (NPA) to 4-nitrophenylate ion using s...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 1(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50187132(3,5-Dimethoxy-4-hydroxybenzoic acid | 4-hydroxy-3,...)
Affinity DataKi:  9.19E+5nM ΔG°:  -4.14kcal/molepH: 7.4 T: 2°CAssay Description:Carbonic anhydrase activity was assayed by following the change in absorbance at 348 nm of 4-nitrophenylacetate (NPA) to 4-nitrophenylate ion using s...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPyruvate kinase PKM(Homo sapiens (Human))
Central University Of Punjab

Curated by ChEMBL
LigandPNGBDBM50187132(3,5-Dimethoxy-4-hydroxybenzoic acid | 4-hydroxy-3,...)
Affinity DataIC50:  1.38E+4nMAssay Description:Inhibition of PKM2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))
Kinki University

Curated by ChEMBL
LigandPNGBDBM50187132(3,5-Dimethoxy-4-hydroxybenzoic acid | 4-hydroxy-3,...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of mushroom tyrosinase using L-tyrosine as substrate preincubated for 10 mins followed by enzyme addition measured after 20 mins by microp...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-(1,3)-fucosyltransferase 7(Homo sapiens (Human))
Schering-Plough Research Institute

LigandPNGBDBM50187132(3,5-Dimethoxy-4-hydroxybenzoic acid | 4-hydroxy-3,...)
Affinity DataIC50: >2.00E+5nMpH: 7.3 T: 2°CAssay Description:A radioligand-binding assay was developed using scintillation proximity assay (SPA) technology. The wheat germ agglutinin SPA beads (Amersham) (0.2 m...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed