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BDBM50187155 (S)-benzyl 1-(5-(4-((4-phenylbutyl)carbamoyl)benzyl)-1,2,4-oxadiazol-3-yl)-6-amino-1-oxohexan-2-ylcarbamate::CHEMBL214148

SMILES: NCCCC[C@H](NC(=O)OCc1ccccc1)C(=O)c1noc(Cc2ccc(cc2)C(=O)NCCCCc2ccccc2)n1

InChI Key: InChIKey=SWHHZDKUVIBHIF-LJAQVGFWSA-N

Data: 1 KI

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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50187155   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Tryptase beta-1/beta-2


(Homo sapiens (Human))
BDBM50187155
PNG
((S)-benzyl 1-(5-(4-((4-phenylbutyl)carbamoyl)benzy...)
Show SMILES NCCCC[C@H](NC(=O)OCc1ccccc1)C(=O)c1noc(Cc2ccc(cc2)C(=O)NCCCCc2ccccc2)n1
Show InChI InChI=1S/C34H39N5O5/c35-21-9-7-16-29(37-34(42)43-24-27-14-5-2-6-15-27)31(40)32-38-30(44-39-32)23-26-17-19-28(20-18-26)33(41)36-22-10-8-13-25-11-3-1-4-12-25/h1-6,11-12,14-15,17-20,29H,7-10,13,16,21-24,35H2,(H,36,41)(H,37,42)/t29-/m0/s1
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
60n/an/an/an/an/an/an/an/a



Celera

Curated by ChEMBL


Assay Description
Inhibition of human beta tryptase


Bioorg Med Chem Lett 16: 4036-40 (2006)


Article DOI: 10.1016/j.bmcl.2006.05.009
BindingDB Entry DOI: 10.7270/Q20864ZV
More data for this
Ligand-Target Pair