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BDBM50187156 (S)-benzyl 1-(5-(4-(benzylcarbamoyl)benzyl)-1,2,4-oxadiazol-3-yl)-6-amino-1-oxohexan-2-ylcarbamate::CHEMBL386704

SMILES: NCCCC[C@H](NC(=O)OCc1ccccc1)C(=O)c1noc(Cc2ccc(cc2)C(=O)NCc2ccccc2)n1

InChI Key: InChIKey=LSDOWXRYVOGCBF-SANMLTNESA-N

Data: 1 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50187156   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Tryptase beta-1/beta-2


(Homo sapiens (Human))
BDBM50187156
PNG
((S)-benzyl 1-(5-(4-(benzylcarbamoyl)benzyl)-1,2,4-...)
Show SMILES NCCCC[C@H](NC(=O)OCc1ccccc1)C(=O)c1noc(Cc2ccc(cc2)C(=O)NCc2ccccc2)n1
Show InChI InChI=1S/C31H33N5O5/c32-18-8-7-13-26(34-31(39)40-21-24-11-5-2-6-12-24)28(37)29-35-27(41-36-29)19-22-14-16-25(17-15-22)30(38)33-20-23-9-3-1-4-10-23/h1-6,9-12,14-17,26H,7-8,13,18-21,32H2,(H,33,38)(H,34,39)/t26-/m0/s1
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
37n/an/an/an/an/an/an/an/a



Celera

Curated by ChEMBL


Assay Description
Inhibition of human beta tryptase


Bioorg Med Chem Lett 16: 4036-40 (2006)


Article DOI: 10.1016/j.bmcl.2006.05.009
BindingDB Entry DOI: 10.7270/Q20864ZV
More data for this
Ligand-Target Pair