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BDBM50187181 (S)-benzyl 1-(5-(4-methoxybenzyl)-1,2,4-oxadiazol-3-yl)-6-amino-1-oxohexan-2-ylcarbamate::CHEMBL213698

SMILES: COc1ccc(Cc2nc(no2)C(=O)[C@H](CCCCN)NC(=O)OCc2ccccc2)cc1

InChI Key: InChIKey=BJXLDDFCVLFRRC-FQEVSTJZSA-N

Data: 1 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50187181   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Tryptase beta-1/beta-2


(Homo sapiens (Human))
BDBM50187181
PNG
((S)-benzyl 1-(5-(4-methoxybenzyl)-1,2,4-oxadiazol-...)
Show SMILES COc1ccc(Cc2nc(no2)C(=O)[C@H](CCCCN)NC(=O)OCc2ccccc2)cc1
Show InChI InChI=1S/C24H28N4O5/c1-31-19-12-10-17(11-13-19)15-21-27-23(28-33-21)22(29)20(9-5-6-14-25)26-24(30)32-16-18-7-3-2-4-8-18/h2-4,7-8,10-13,20H,5-6,9,14-16,25H2,1H3,(H,26,30)/t20-/m0/s1
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
770n/an/an/an/an/an/an/an/a



Celera

Curated by ChEMBL


Assay Description
Inhibition of human beta tryptase


Bioorg Med Chem Lett 16: 4036-40 (2006)


Article DOI: 10.1016/j.bmcl.2006.05.009
BindingDB Entry DOI: 10.7270/Q20864ZV
More data for this
Ligand-Target Pair